Topographic patterns and stroke subtypes according to progressive motor deficits in lacunar syndrome

Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association
Yong Bum KimPil-Wook Chung

Abstract

Although progressive hemiparesis occurs frequently in acute ischemic stroke, the topography and mechanisms associated with progressive motor deficit (PMD) remain unclear. The aim of this study was to identify the differences in PMD according to lesion location and the presumed underlying pathogenesis in patients with lacunar motor syndrome. Consecutive patients experiencing acute lacunar motor syndrome within 24 hours of stroke onset were included. Topographic patterns, risk factors, and presumed stroke mechanisms were compared between patients with PMD and those without PMD. Of the 168 patients in the study group, 47 (28.0%) had PMD. Baseline National Institutes of Health Stroke Scale score (P = .034) and female sex (P = .005) were associated with PMD on univariate analysis. Deep perforating artery infarct was more frequently associated with PMD (35.8%) compared with large artery disease (27.3%) and cardioembolism (5.3%). Multiple logistic analysis found that deep perforating artery infarct was independently associated with PMD (odds ratio, 2.87; 95% confidence interval, 1.26-6.5; P = .012). Deep perforating artery infarct is the major cause of PMD. In patients with lacunar syndrome, the pattern of PMD varies according to the ...Continue Reading

References

Aug 1, 1978·Neurology·J P MohrH L Bleich
Nov 1, 1994·Stroke; a Journal of Cerebral Circulation·P LydenJ Marler
Apr 30, 1998·Archives of Neurology·H YamamotoG van Melle
Jun 20, 1998·Neurology·L TatuH Duvernoy
Jan 28, 1999·Neurology·K NakamuraM Fujishima
Apr 6, 2002·Stroke; a Journal of Cerebral Circulation·Mar CastellanosAntoni Dávalos
Jun 8, 2002·Stroke; a Journal of Cerebral Circulation·Wolfgang Steinke, Stephan C Ley
Aug 3, 2002·Stroke; a Journal of Cerebral Circulation·Richard P GerratyStephen M Davis
Jul 3, 2003·Annals of Neurology·Dong-Wha KangSteven Warach
Nov 11, 2003·Journal of the Neurological Sciences·Vincent C T MokKa Sing Wong
Jan 7, 2004·Journal of the Neurological Sciences·Noriko MatsumotoKazuo Minematsu
Jan 14, 2004·Cerebrovascular Diseases·Philip BirschelDavid Barer
Feb 28, 2004·European Neurology·Heinrich J AudebertRoman L Haberl
Apr 6, 2004·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·E KumralY Alper
Mar 16, 2005·Archives of Neurology·Christian WeimarUNKNOWN German Stroke Study Collaboration
Oct 18, 2005·Journal of Neurology, Neurosurgery, and Psychiatry·T SeifertF Fazekas
Nov 12, 2005·Cerebrovascular Diseases·Vadim G KarepovNatan M Bornstein
Nov 18, 2005·Journal of Neurology, Neurosurgery, and Psychiatry·P H LeeK Huh
Sep 11, 2007·Neuroimaging Clinics of North America·Colin P Derdeyn
Feb 12, 2008·European Neurology·E KalowskaO B Paulson
Feb 28, 2008·Cerebrovascular Diseases·Soo Kyoung KimGyeong-Moon Kim
Jul 17, 2008·European Neurology·Yoshinari NagakaneTakemori Yamawaki
Apr 4, 2009·Cerebrovascular Diseases·P AmarencoM G Hennerici

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