PMID: 76678Mar 20, 1978Paper

Topographical studies on intestinal microvillous leucine beta-naphthylamidase on the outer membrane surface

The Journal of Membrane Biology
Y Takesue, Y Nishi


The location of leucine beta-naphthylamidase on the outer surface of the microvillous membrane of rabbit small intestine was examined by analyzing the interaction of antibodies against leucine beta-naphthylamidase or another microvillous enzyme, sucrase-isomaltase complex, with microvillous vesicles having different relative amounts of these enzymes, in respect to vesicle agglutination, inhibition of enzyme activity, and electron-microscopic morphology. The results obtained indicate that leucine beta-naphthylamidase, or at least its antigenic sites, protrude about 10 nm from the outer surface of the microvillous membrane.


Aug 11, 1977·Biochimica Et Biophysica Acta·Y TakesueY Nishi
Jan 1, 1978·Journal of Ultrastructure Research·Y Nishi, Y Takesue
Oct 17, 1975·Biochimica Et Biophysica Acta·H SigristG Semenza
Apr 1, 1969·Journal of Biochemistry·Y Takesue
Feb 1, 1961·The Journal of Biophysical and Biochemical Cytology·J H LUFT

Related Concepts

Antigenic Specificity
Antibody Dissociation
Structure of Intestinal Gland
Methoxyleucine Aminopeptidase
Electron Microscopy
Chinchilla Rabbits
Sucrase-Isomaltase Complex

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