Topography mapping of whole body adipose tissue using A fully automated and standardized procedure

Journal of Magnetic Resonance Imaging : JMRI
Christian WürslinFritz Schick

Abstract

To obtain quantitative measures of human body fat compartments from whole body MR datasets for the risk estimation in subjects prone to metabolic diseases without the need of any user interaction or expert knowledge. Sets of axial T1-weighted spin-echo images of the whole body were acquired. The images were segmented using a modified fuzzy c-means algorithm. A separation of the body into anatomic regions along the body axis was performed to define regions with visceral adipose tissue present, and to standardize the results. In abdominal image slices, the adipose tissue compartments were divided into subcutaneous and visceral compartments using an extended snake algorithm. The slice-wise areas of different tissues were plotted along the slice position to obtain topographic fat tissue distributions. Results from automatic segmentation were compared with manual segmentation. Relatively low mean deviations were obtained for the class of total tissue (4.48%) and visceral adipose tissue (3.26%). The deviation of total adipose tissue was slightly higher (8.71%). The proposed algorithm enables the reliable and completely automatic creation of adipose tissue distribution profiles of the whole body from multislice MR datasets, reducing w...Continue Reading

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Citations

Jun 5, 2013·Best Practice & Research. Clinical Endocrinology & Metabolism·Jürgen MachannFranz Wolfgang Hirsch
Apr 8, 2014·Academic Radiology·Michalis MantatzisPanos Prassopoulos
Sep 27, 2012·Journal of Magnetic Resonance Imaging : JMRI·Anand A JoshiKrishna S Nayak
Oct 15, 2013·NMR in Biomedicine·H H Hu, H E Kan
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Feb 16, 2013·Food Chemistry·Guylaine CollewetPierrick Haffray
Sep 11, 2016·La Radiologia medica·Sergios GatidisFabian Bamberg
Apr 23, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Erika J UlbrichMichael A Fischer
Nov 30, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Houchun H HuS Sendhil Velan
Jul 30, 2020·The Journal of Clinical Endocrinology and Metabolism·Róbert WagnerMartin Heni
Aug 23, 2020·The Journal of Clinical Endocrinology and Metabolism·Christoph HoffmannAnja Moller
Nov 28, 2017·Topics in Magnetic Resonance Imaging : TMRI·Cheng William HongClaude B Sirlin
Jun 14, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Houchun Harry HuClaude Sirlin
Apr 17, 2020·Nature Communications·Stephanie KullmannMartin Heni
Oct 8, 2020·Journal of Neuroendocrinology·Stephanie KullmannHubert Preissl
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Apr 17, 2021·Metabolism: Clinical and Experimental·Apostolia LamprinouRobert Wagner

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