PMID: 3213951Jan 1, 1988Paper

Topography of basal glucose utilization in rat thalamus and hypothalamus determined with (1-14C)-glucose

Anatomy and Embryology
O BrüstleW E Stumpf

Abstract

High resolution autoradiography was used to study the basal pattern of glucose-utilization in the rat thalamus and hypothalamus. Rats were injected via chronic jugular catheter with (1-14C)-glucose and sacrificed 30 min later. The high resolution thaw-mount autoradiographic procedure, using 4 micron frozen sections and nuclear emulsion, permitted discrimination of regional variations in glucose-utilization that have not yet been described. Quantitative data were obtained by means of digital image analysis and computerized densitometry. In the thalamus, high activity was present in the anterodorsal, anteroventral, laterodorsal and reticular nuclei, while low activity was found in the mediodorsal and paraventricular nuclei. The autoradiographic pattern of glucose utilization in the thalamus corresponds largely to classical cytoarchitectonic subdivisions. In the hypothalamus, the median eminence, arcuate nucleus, and periventricular nucleus showed the lowest activity, whereas certain parts of the lateral hypothalamus appeared high. Very high activity was present in mammillary nuclei. The described detailed anatomical data of glucose-utilization may provide insights into the functional circuitry of thalamic and hypothalamic systems...Continue Reading

References

Jan 15, 1977·The Journal of Comparative Neurology·J E Krettek, J L Price
Apr 15, 1977·The Journal of Comparative Neurology·J E Krettek, J L Price
Aug 1, 1987·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·C Pilgrim, W E Stumpf
Jan 1, 1985·The American Journal of Physiology·R A HawkinsL S Hibbard
Mar 1, 1966·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·W E Stumpf, L J Roth
Nov 1, 1983·The American Journal of Physiology·D M LuR A Hawkins
Jan 1, 1981·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·L Sokoloff

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Citations

Jan 14, 2012·Progress in Histochemistry and Cytochemistry·Walter E Stumpf

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