Topography of corticopontine remodelling after cortical lesions in newborn rats

The Journal of Comparative Neurology
G Kartje-TillotsonA J Castro

Abstract

Autoradiographic and axonal degeneration staining techniques were combined in individual animals to study the distribution of corticopontine fibers. In normal animals, forelimb and hindlimb motor cortical projections terminated somatotopically within the ipsilateral pontine nuclei. Sparse crossed projections also displayed a somatotopic pattern. After unilateral sensorimotor cortical lesions in newborn rats, an increase in the crossed corticopontine fibers arising from the opposite unablated motor cortex was observed at maturity. These fibers distributed in a topographic pattern similar to the normal ipsilateral corticopontine pattern; forelimb motor cortical projections terminated rostral to hindlimb motor cortical fibers. The specific distribution of the anomalous fibers suggests that they constitute a functional pathway.

References

Jun 1, 1979·The Journal of Comparative Neurology·D O Frost, G E Schneider
Aug 6, 1976·Brain Research·M J Mustari, R D Lund
Mar 1, 1986·Brain Research·E J NeafseyR R Terreberry
Jul 1, 1985·The Journal of Comparative Neurology·K A Crutcher, J P Chandler
Oct 20, 1981·The Journal of Comparative Neurology·R A BurneD J Woodward
Jan 10, 1984·The Journal of Comparative Neurology·R S SwensonA J Castro
Sep 1, 1983·The Journal of Comparative Neurology·A J Castro, G A Mihailoff
Aug 1, 1980·Neuroscience Letters·S H NahS K Leong
Jan 28, 1982·Brain Research·E J Neafsey, C Sievert
Jul 1, 1982·The Journal of Comparative Neurology·R Wiesendanger, M Wiesendanger
May 1, 1980·Brain Research Bulletin·C E AdamsD J Woodward

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Citations

Jul 11, 2000·The Journal of Comparative Neurology·M A KingsburyB L Finlay
Nov 1, 1988·Behavioural Brain Research·J F HobbelenM W Van Hof
Jan 1, 1989·Progress in Neurobiology·B Kolb, I Q Whishaw
Jan 31, 2012·Developmental Neuroscience·Akira YoshikawaKengo Funakoshi
Nov 29, 2008·Stroke; a Journal of Cerebral Circulation·Catherine M PapadopoulosWilliam A Wolf
Aug 15, 1992·The Journal of Comparative Neurology·B KolbD van der Kooy
Dec 15, 1990·The Journal of Comparative Neurology·R Z Kuang, K Kalil
May 13, 2005·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Andrew B SeymourGwendolyn L Kartje
Feb 7, 2003·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Christoph WiessnerMartin E Schwab
Dec 18, 2013·The European Journal of Neuroscience·Yu-Qiu JiangJohn H Martin
May 13, 2006·Experimental Neurology·Eleftherios S PapathanasiouGwendolyn L Kartje
Sep 10, 2013·Neuroscience Research·Tatsuya Umeda, Kengo Funakoshi
Nov 21, 2013·Neuroscience Research·Oraphan WanakhachornkraiTadashi Isa
Apr 8, 1996·The Journal of Comparative Neurology·L AcarinA J Castro

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