PMID: 2224514Jul 2, 1990Paper

Topography of movement-related cortical potentials is abnormal in Parkinson's disease

Brain Research
I M TarkkaM Hallett

Abstract

We studied the scalp-recorded, movement-related cortical potentials occurring immediately before and after the onset of movement in 5 patients with asymmetric Parkinson's disease. The topographic distribution of the initial slope of motor potential (isMP) was diffuse for voluntary finger movements of the more affected hand but normal for movements of the less affected hand. The frontal peak of motor potential (fpMP) was located more posterior in patients than in normal subjects. The peak amplitudes of the potentials were normal in all patients. The topographic abnormalities might reflect inadequate excitatory activity from the basal ganglia to the primary motor cortex and the supplementary motor area.

References

Jul 14, 1976·Biological cybernetics·L DeeckeH H Kornhuber
Apr 1, 1986·Electroencephalography and Clinical Neurophysiology·G BarrettR Neshige
Apr 1, 1986·Electroencephalography and Clinical Neurophysiology·G BarrettR Neshige
Mar 1, 1985·Electroencephalography and Clinical Neurophysiology·G BarrettR Neshige
Feb 1, 1989·Brain : a Journal of Neurology·J P DickC D Marsden
Aug 1, 1986·Brain : a Journal of Neurology·R BeneckeC D Marsden
Aug 1, 1980·Electroencephalography and Clinical Neurophysiology·H ShibasakiA M Halliday

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Citations

Sep 1, 1996·Journal of the Neurological Sciences·P PraamstraM W Horstink
Feb 1, 1994·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·I M Tarkka
Feb 1, 1997·Electroencephalography and Clinical Neurophysiology·A IkedaJ Kimura
Jan 1, 1995·Movement Disorders : Official Journal of the Movement Disorder Society·K BötzelW Paulus
Jan 1, 1990·Brain Topography·K Matsumoto
Aug 1, 1993·Acta Neurologica Scandinavica·I M TarkkaM Hallett

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