TOPPE: A framework for rapid prototyping of MR pulse sequences

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
Jon-Fredrik Nielsen, Douglas C Noll

Abstract

To introduce a framework for rapid prototyping of MR pulse sequences. We propose a simple file format, called "TOPPE", for specifying all details of an MR imaging experiment, such as gradient and radiofrequency waveforms and the complete scan loop. In addition, we provide a TOPPE file "interpreter" for GE scanners, which is a binary executable that loads TOPPE files and executes the sequence on the scanner. We also provide MATLAB scripts for reading and writing TOPPE files and previewing the sequence prior to hardware execution. With this setup, the task of the pulse sequence programmer is reduced to creating TOPPE files, eliminating the need for hardware-specific programming. No sequence-specific compilation is necessary; the interpreter only needs to be compiled once (for every scanner software upgrade). We demonstrate TOPPE in three different applications: k-space mapping, non-Cartesian PRESTO whole-brain dynamic imaging, and myelin mapping in the brain using inhomogeneous magnetization transfer. We successfully implemented and executed the three example sequences. By simply changing the various TOPPE sequence files, a single binary executable (interpreter) was used to execute several different sequences. The TOPPE file form...Continue Reading

References

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Jun 6, 1998·Journal of Magnetic Resonance·J H DuynJ W van der Veen
Jan 1, 1991·IEEE Transactions on Medical Imaging·J PaulyA Macovski
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Apr 14, 2012·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Signe J VannesjoKlaas P Pruessmann
Mar 15, 2013·Nature·Dan MaMark A Griswold
Mar 8, 2014·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Gopal VarmaDavid C Alsop
Mar 11, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jeremy F MaglandFelix W Wehrli
Jul 15, 2015·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Jon-Fredrik Nielsen, Douglas C Noll
Jun 9, 2016·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kelvin J LaytonMaxim Zaitsev

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Citations

Mar 12, 2020·Bioelectromagnetics·Jonna WilénKjell Hansson Mild
Apr 14, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Steven T WhitakerJeffrey A Fessler
Aug 28, 2020·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Amos A Cao, Douglas C Noll
Oct 22, 2019·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Cristoffer CordesMatthias Günther
May 8, 2021·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Kai HerzMoritz Zaiss
Oct 12, 2019··Keerthi RaviSairam Geethanath

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