PMID: 11923100Mar 30, 2002Paper

Torpor-associated fluctuations in surfactant activity in Gould's wattled bat

Biochimica Et Biophysica Acta
J R CoddSandra Orgeig

Abstract

The primary function of pulmonary surfactant is to reduce the surface tension (ST) created at the air-liquid interface in the lung. Surfactant is a complex mixture of lipids and proteins and its function is influenced by physiological parameters such as metabolic rate, body temperature and breathing. In the microchiropteran bat Chalinolobus gouldii these parameters fluctuate throughout a 24 h period. Here we examine the surface activity of surfactant from warm-active and torpid bats at both 24 degrees C and 37 degrees C to establish whether alterations in surfactant composition correlate with changes in surface activity. Bats were housed in a specially constructed bat room at Adelaide University, at 24 degrees C and on a 8:16 h light:dark cycle. Surfactant was collected from bats sampled during torpor (25<T(b)<28 degrees C), and while active (T(b)>35 degrees C). Alterations in the lipid composition of surfactant occur with changes in the activity cycle. Most notable is an increase in surfactant cholesterol (Chol) with decreases in body temperature [Codd et al., Physiol. Biochem. Zool. 73 (2000) 605-612]. Surfactant from active bats was more surface active at higher temperatures, indicated by lower ST(min) and less film area com...Continue Reading

References

Dec 1, 1989·Journal of Applied Physiology·S SchürchF Possmayer
Nov 1, 1988·Chemistry and Physics of Lipids·B D Fleming, K M Keough
Sep 29, 1998·Clinical and Experimental Pharmacology & Physiology·C B DanielsS Orgeig
Nov 14, 1998·Biochimica Et Biophysica Acta·R VeldhuizenF Possmayer
Nov 14, 1998·Biochimica Et Biophysica Acta·T E Weaver
Nov 14, 1998·Biochimica Et Biophysica Acta·S SchürchH Bachofen
Nov 14, 2000·Physiological and Biochemical Zoology : PBZ·J R CoddS Orgeig
May 23, 2001·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·S Orgeig, C B Daniels
May 23, 2001·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·S SchürchF Possmayer

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Citations

Aug 14, 2003·Biochemical and Biophysical Research Communications·Jonathan R CoddSamuel Schürch
Jun 21, 2005·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Natalie J MillerSandra Orgeig
Feb 16, 2006·Respiratory Physiology & Neurobiology·Natalie J MillerSandra Orgeig
Apr 6, 2004·Journal of Applied Physiology·Laura M Y YuA Wilhelm Neumann
Jul 23, 2005·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Carol J LangChristopher B Daniels
Apr 5, 2017·Frontiers in Pediatrics·John S Torday, Heber C Nielsen
Oct 12, 2005·Biochimica Et Biophysica Acta·Lasantha GunasekaraMatthias Amrein
Aug 1, 2006·Respiratory Physiology & Neurobiology·Natalie J FootChristopher B Daniels
Jun 1, 2007·Comparative Biochemistry and Physiology. Part D, Genomics & Proteomics·Sally PotterChristopher B Daniels
Nov 27, 2007·Biochimica Et Biophysica Acta·Lasantha GunasekaraMatthias W Amrein

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