PMID: 16521915Mar 9, 2006Paper

Total antioxidant capacity of blood plasma in healthy men and in men with coronary heart disease

Przegla̧d lekarski
Anna GawronTomasz Kostka

Abstract

The aim of the study was to determine the level of total antioxidant capacity (TAC) of blood plasma in healthy men and in men with coronary heart disease differentiated by their level of physical activity. The study was carried out in the two groups of age-adjusted men. Group I comprised 100 healthy men aged 56.6 +/- 8.5 years and group II involved 100 men with identified coronary heart disease aged 56.6 +/- 7.2 years. BMI was determined in every participant. Level of energy expediture was determined by calculating the amount of hours per week spent for different recreational sports activities. Spectrophotometric method FRAP (Ferric Reducing Ability of Plasma) was applied to estimate total antioxidant capacity of blood plasma. Values of absorbance describing level of total antioxidant capacity of blood plasma in 1', 3' and 10' minut of reaction time window differed between groups. Men with coronary heart disease were characterised by higher antioxidant defense system than healthy ones. Energy expediture expressed in kcal per week was statistically higher in healthy subjects. In healthy men positive correlation was found between level of total antioxidant capacity (in 1', 3' and 10' minut of reaction time window) and BMI (p< or ...Continue Reading

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