PMID: 7089054May 1, 1982

Total body neutron activation analysis of calcium: calibration and normalisation

Physics in Medicine and Biology
N S KennedyP Tothill

Abstract

An irradiation system has been designed, using a neutron beam from a cyclotron, which optimises the uniformity of activation of calcium. Induced activity is measured in a scanning, shadow-shield whole-body counter. Calibration has been effected and reproducibility assessed with three different types of phantom. Corrections were derived for variations in body height, depth and fat thickness. The coefficient of variation for repeated measurements of an anthropomorphic phantom was 1.8% for an absorbed dose equivalent of 13 mSv (1.3 rem). Measurements of total body calcium in 40 normal adults were used to derive normalisation factors which predict the normal calcium in a subject of given size and age. The coefficient of variation of normalised calcium was 6.2% in men and 6.6% in women, with the demonstration of an annual loss of 1.5% after the menopause. The narrow range should make single measurements useful for diagnostic purposes.

References

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Citations

Jan 1, 1984·Calcified Tissue International·L E JimenezG F Joplin
Sep 1, 1986·Calcified Tissue International·G WilliamsG F Joplin
Oct 1, 1985·Paraplegia·R K StrachanN S Kennedy
Apr 1, 1984·Annals of the Rheumatic Diseases·D M ReidG Nuki
Nov 1, 1983·The British Journal of Radiology·P TothillD Sutton
Jan 1, 1983·Metabolic Bone Disease & Related Research·R EastellP Tothill
Mar 1, 1983·Physics in Medicine and Biology·N S KennedyP Tothill
Sep 1, 1984·Physics in Medicine and Biology·D R Chettle, J H Fremlin
Nov 1, 1986·Clinical Physics and Physiological Measurement : an Official Journal of the Hospital Physicists' Association, Deutsche Gesellschaft Für Medizinische Physik and the European Federation of Organisations for Medical Physics·P TothillG Nuki
Jan 1, 1986·Journal of the Royal Society of Medicine·D M Reid
Jun 1, 1987·Physics in Medicine and Biology·J J NicollG Nuki
May 1, 1989·Physics in Medicine and Biology·P Tothill
Jun 1, 1983·Physics in Medicine and Biology·M A SmithP Tothill

Related Concepts

Calcium
Neutron Activation Analysis

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