Total number of cells in the human newborn telencephalic wall

Neuroscience
C C LarsenBente Pakkenberg

Abstract

The total cell numbers were estimated in the neocortical part of the human telencephalon in 10 normal brains of newborn babies within four major developmental zones: the cortical plate/marginal zone, the subplate, the intermediate zone and the ventricular/subventricular zone. Furthermore, the total number of neuron and glial cells was estimated in the cortical plate. The gestational ages ranged from 38 + 0-42 + 5 weeks + days of gestation. The mean total cell number was 32.6 x 10(9) (coefficient of error = 0.04) and the total number of neurons in the cortical plate 19.8 x 10(9) (coefficient of error = 0.06). This indicates that the total number of neocortical neurons equals the total number in the adults, which, however, is not the case for the glial cells.

References

Jan 1, 1988·Biology of the Neonate·N Herschkowitz
Jul 8, 1988·Science·P Rakic
Oct 1, 1973·Archives of Disease in Childhood·J Dobbing, J Sands
Jul 28, 1997·The Journal of Comparative Neurology·B Pakkenberg, H J Gundersen
Nov 11, 1998·Nature Medicine·P S ErikssonF H Gage
May 29, 1999·Journal of Microscopy·H J Gundersen Nielsen J
Oct 16, 1999·Science·E GouldC G Gross
Dec 7, 2000·Journal of Microscopy·K A Dorph-PetersenE B Jensen
Jan 12, 2002·Current Opinion in Pharmacology·Daniel A Peterson
Jan 1, 2003·Cerebral Cortex·Grethe Badsberg SamuelsenBente Pakkenberg

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Citations

Feb 1, 2008·Cerebral Cortex·Kiho ImSun I Kim
Mar 29, 2014·The New England Journal of Medicine·Rich StonerEric Courchesne
Aug 30, 2006·Proceedings of the National Academy of Sciences of the United States of America·Chet C SherwoodPatrick R Hof
May 6, 2010·American Journal on Intellectual and Developmental Disabilities·Mohammed Rachidi, Carmela Lopes
Feb 4, 2011·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Kol Jia Yong, Benedict Yan
Sep 28, 2010·Brain Research·Cynthia Mills Schumann, Christine Wu Nordahl
Jun 5, 2007·Neurobiology of Aging·D P PelvigB Pakkenberg
Aug 1, 2014·Frontiers in Human Neuroscience·Solveig WalløeKatrine Fabricius
Oct 14, 2016·Cerebral Cortex·Majken KjærBente Pakkenberg
Sep 1, 2017·Proceedings. Biological Sciences·Christine J CharvetBarbara L Finlay
Jan 11, 2020·Frontiers in Neuroanatomy·Zhenzhen YouThierry Delzescaux

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