Total Skin Sparing (Nipple Sparing) Mastectomy: What is the Evidence?

Surgical Oncology Clinics of North America
Amar Gupta, Patrick I Borgen

Abstract

The surgical treatment of breast cancer has evolved from radical mastectomy with routine removal of the nipple-areolar complex (NAC) to breast conservative therapy with preservation of the breast and NAC. Each step along this evolutionary process was met with criticism, skepticism, controversy, anger, emotion, and often bitter and impassioned debate. Today we find ourselves at yet another therapeutic decision point: the management of the skin of the nipple-areolar complex in mastectomy. Enhanced understanding of the pathogenesis of breast cancer coupled with rising interest in improved cosmesis has led to the investigation of the skin-sparing and nipple-sparing mastectomy as potential modifications to conventional mastectomy.

References

Nov 26, 2005·American Journal of Surgery·Aaron G MarguliesV Suzanne Klimberg
Nov 7, 2006·Journal of the American College of Surgeons·Virgilio SacchiniPatrick I Borgen
Aug 22, 2007·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·K P Benediktsson, L Perbeck
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Mar 25, 2008·Breast Cancer Research and Treatment·J Y PetitR Orecchia
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Dec 1, 2009·The Breast : Official Journal of the European Society of Mastology·Alexandre Mendonça MunhozMarcus Castro Ferreira

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Citations

Jul 27, 2015·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Riccardo PonzoneLaura Martincich
Oct 26, 2011·Nature Reviews. Clinical Oncology·Jean-Yves PetitMario Rietjens
Aug 13, 2014·World Journal of Clinical Oncology·Alexandre Mendonça MunhozRolf Gemperli
Jun 21, 2012·JAAPA : Official Journal of the American Academy of Physician Assistants·Brian K Yorkgitis, Amy J Goldberg

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