Total synthesis of (±)-sorocenol B employing nanoparticle catalysis.

Organic Letters
Huan Cong, John A Porco

Abstract

The total synthesis of (±)-sorocenol B has been accomplished featuring key steps including silver nanoparticle (AgNP)-catalyzed Diels-Alder cycloaddition and late-stage Pd(II)-catalyzed oxidative cyclization. The synthetic natural product exhibited low micromolar cytotoxic activity against a number of human cancer cell lines.

References

Dec 15, 2005·Journal of the American Chemical Society·Raissa M TrendBrian M Stoltz
Jan 24, 2006·Bioscience, Biotechnology, and Biochemistry·Jun Nishida, Jun Kawabata
Jul 20, 2007·Chemistry & Biodiversity·Qing-Jian ZhangDe-Quan Yu
Jun 26, 2008·Journal of the American Chemical Society·Huan CongJohn A Porco
Mar 4, 2010·Organic Letters·Christian Gunawan, Mark A Rizzacasa
May 7, 2010·Journal of the American Chemical Society·Huan CongJohn A Porco
Feb 8, 2011·Chemical Society Reviews·Will R Gutekunst, Phil S Baran
Mar 11, 2011·Chemical Society Reviews·Lindsay McMurrayMatthew J Gaunt
Feb 22, 2012·ACS Catalysis·Huan Cong, John A Porco
Apr 11, 2012·Organic & Biomolecular Chemistry·Sompong BoonsriMark A Rizzacasa

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Citations

Jan 13, 2016·Organic Letters·Lei GaoXiaoguang Lei
Jan 7, 2016·Journal of the American Chemical Society·Chao QiJohn A Porco
Oct 30, 2016·Journal of Natural Products·Valentina IovineAndrea Calcaterra
Jul 22, 2014·Angewandte Chemie·Jianguang HanXiaoguang Lei
Mar 16, 2021·The Journal of Organic Chemistry·Si-Yuan LuoGui-Hua Tang
Feb 20, 2014·Journal of the American Chemical Society·Chao QiJohn A Porco

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