Total synthesis of zincophorin and its methyl ester

The Journal of Organic Chemistry
Magali DefosseuxJanine Cossy

Abstract

A total synthesis of the naturally occurring ionophore zincophorin has been realized. The route features an intramolecular oxymercuration of a cyclopropanemethanol and a Carroll-Claisen rearrangement for the respective elaboration of the C1-C12 and C13-C25 subunits, which have been assembled by using a highly diastereoselective titanium-mediated aldol condensation.

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Oct 25, 2001·The Journal of Organic Chemistry·Janine CossyChristophe Meyer
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Oct 24, 2003·Organic Letters·Magali DefosseuxJanine Cossy

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Citations

Apr 29, 2011·Journal of the American Chemical Society·Tyler J HarrisonJames L Leighton
Nov 6, 2007·The Journal of Organic Chemistry·Zhenlei SongAndrew G Lohse
Aug 1, 2009·Natural Product Reports·Zhenlei SongRichard P Hsung
Aug 19, 2015·European Journal of Medicinal Chemistry·Xiang-Yang QinWei-Dong Zhang
Jul 15, 2015·Journal of the American Chemical Society·Zachary A KasunMichael J Krische
Mar 8, 2017·Journal of the American Chemical Society·Liang-An ChenJames L Leighton
Jun 5, 2013·Chemistry : a European Journal·François GodinYvan Guindon
Feb 13, 2018·Chemistry : a European Journal·Marllon Nascimento de OliveiraJanine Cossy
May 18, 2010·The Journal of Organic Chemistry·Alexander B RudineCarl C Wamser
Jan 31, 2015·Organic Letters·Damien BrandtJanine Cossy

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