Total Weight Loss as the Outcome Measure of Choice After Roux-en-Y Gastric Bypass

Obesity Surgery
Ricard CorcellesPhilip R Schauer

Abstract

Currently, there is no agreement on the best method to describe weight loss (WL) after bariatric surgery. The aim of this study is to evaluate short-term outcomes using percent of total body weight loss (%TWL). A single-institution retrospective study of 2420 patients undergoing Roux-en-Y gastric bypass (RYGB) was performed. Suboptimal WL was defined as %TWL < 20 % at 12 months. Mean preoperative BMI was 46.8 ± 7.8 kg/m(2). One year after surgery, patients lost an average 14.1 kg/m(2) units of body mass index (BMI), 30.0 ± 8.5 %TWL, and 68.5 ± 22.9 %EWL. At 6 and 12 months after RYGB, mean BMI and percent excess WL (%EWL) significantly improved for all baseline BMI groups (p < 0.01, BMI; p = 0.01, %EWL), whereas mean %TWL was not significantly different among baseline BMI groups (p = 0.9). The regression analysis between each metric outcome and preoperative BMI demonstrated that preoperative BMI did not significantly correlate with %TWL at 1 year (r = 0.04, p = 0.3). On the contrary, preoperative BMI was strongly but negatively associated with the %EWL (r = -0.52, p < 0.01) and positively associated with the BMI units lost at 1 year (r = 0.56, p < 0.01). In total, 11.3 % of subjects achieved <20 %TWL at 12 months and were consi...Continue Reading

References

Dec 1, 1985·Annals of Internal Medicine·G G Harrison
Sep 12, 2000·The Annals of Pharmacotherapy·M P Pai, F P Paloucek
May 3, 2001·The New England Journal of Medicine·J TuomilehtoUNKNOWN Finnish Diabetes Prevention Study Group
Sep 23, 2006·Obesity Surgery·Yunsheng MaJohn J Kelly
Oct 25, 2006·Annals of Surgery·Nicolas V ChristouLloyd D Maclean
Mar 16, 2007·International Journal of Obesity : Journal of the International Association for the Study of Obesity·J KarlssonM Sullivan
Jul 31, 2007·Obesity Surgery·Mervyn DeitelJohn Melissas
Aug 24, 2007·The New England Journal of Medicine·Ted D AdamsSteven C Hunt
Jul 29, 2008·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Marc BesslerDaniel G Davis
Mar 12, 2009·Obesity Surgery·Ramsey M DallalLeonard E Braitman
Jun 30, 2009·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Gladys W StrainPaul Christos
Jul 28, 2009·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Shahzeer KarmaliArya M Sharma
Jul 31, 2009·The New England Journal of Medicine·UNKNOWN Longitudinal Assessment of Bariatric Surgery (LABS) ConsortiumBruce Wolfe
Aug 13, 2011·Obesity Surgery·Masha LivhitsMelinda Maggard Gibbons
Jan 23, 2013·Obesity Surgery·Henry Buchwald, Danette M Oien
Sep 3, 2013·Obesity Surgery·Shahzeer KarmaliDaniel W Birch
Oct 2, 2014·JAMA Surgery·Anita P CourcoulasDavid E Arterburn
Dec 18, 2014·Obesity Surgery·Jake P MannJulian H Barth
Jul 16, 2015·Diabetes Technology & Therapeutics·Ali AminianStacy A Brethauer

❮ Previous
Next ❯

Citations

Apr 19, 2017·The Journal of Clinical Endocrinology and Metabolism·Pierre Bel LassenKarine Clément
Apr 5, 2018·Journal of the American Podiatric Medical Association·Mena BoulesMatthew Kroh
Nov 5, 2019·Obesity Surgery·Vera VoorwindeMaartje M van Stralen
Jun 18, 2018·Obesity Surgery·Agustina VigilanteFederico Moser
Oct 12, 2018·Clinical Endoscopy·Pichamol Jirapinyo, Christopher C Thompson
Nov 16, 2019·Current Diabetes Reports·Hope T JacksonFatima Cody Stanford
Apr 25, 2020·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Mette S NielsenAnders Sjödin
Sep 29, 2020·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Yinfang TuHaoyong Yu
Oct 5, 2017·Obesity Surgery·Marcos A BerryRodrigo Alonso
Jul 25, 2018·Obesity Surgery·C M M CehaS W Nienhuijs
Aug 10, 2018·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Martin MüllerDino Kröll
Jul 1, 2019·Obesity Surgery·Brandon T GroverMatthew T Baker
Jan 4, 2020·Obesity Surgery·E A KatsareliG V Dedoussis
Sep 24, 2020·Obesity Surgery·Yazmin JohariPaul Burton
Sep 27, 2018·Obesity Surgery·Rita Bettencourt-SilvaDavide Carvalho
Sep 7, 2018·JCI Insight·Juan de Toro-MartínMarie-Claude Vohl
Jan 6, 2021·Obesity Surgery·Marc BeisaniUNKNOWN Members of the Obesity Section of the Spanish Surgical Association Collaborative Group
May 9, 2021·Obesity Surgery·Beata M M ReiberSjoerd C Bruin
May 13, 2021·International Journal of Obesity : Journal of the International Association for the Study of Obesity·Pouya IranmaneshMehran Anvari
May 31, 2021·Clinical Obesity·Marleen M RomeijnMarieke van de Wal
Mar 12, 2021·The Journal of Clinical Endocrinology and Metabolism·Emanuele MuracaMatteo Villa
Nov 7, 2020·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Arnold W J M van de LaarMax Nieuwdorp
Jun 25, 2021·Bariatric Surgical Practice and Patient Care·Dustin BaldwinMario Masrur
Sep 4, 2021·Plastic and Reconstructive Surgery. Global Open·Joshua T HendersonKerri M Woodberry

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.