Tough love: accommodating intracellular bacteria through directed secretion of antimicrobial peptides during the nitrogen-fixing symbiosis

Current Opinion in Plant Biology
Christina Stonoha-Arther, Dong Wang

Abstract

The symbiosis formed by nitrogen-fixing bacteria with plant hosts mainly in the legume family involves a very intimate interaction. Within the symbiotic organ (the nodule) the bacteria are fully internalized by the host cell to become an intracellular organelle surrounded by a host-derived membrane. This arrangement is probably necessary for the efficient provision of energy and the sequestration of free oxygen molecules, two conditions required for sustained nitrogen fixation. Recent advances made in model legume species, such as Medicago truncatula, are beginning to uncover the genetic components allowing rhizobia to access the host cytoplasm and establish chronic intracellular infections without overt detrimental effects. It is now known that the rhizobial compartment in M. truncatula cells, the symbiosome, retains some features of the extracellular space as the target for a redirected host protein secretory pathway. A set of vesicle trafficking proteins function specifically in symbiotic cells to ensure the faithful delivery of secretory proteins to the intracellular bacteria, or bacteroid. This system is co-opted from the more ancient association with arbuscular mycorrhizal fungi found in most land plants, highlighting the...Continue Reading

References

Jan 25, 2002·Nature·Michael Zasloff
Dec 12, 2002·Chemical Reviews·Mark PaetzelRoss E Dalbey
Sep 2, 2003·Nature Reviews. Immunology·Tomas Ganz
Feb 5, 2004·Electrophoresis·Christina M CatalanoD Janine Sherrier
Jul 22, 2004·Plant Physiology·Michelle A GrahamKathryn A VandenBosch
Mar 21, 2006·Proceedings of the National Academy of Sciences of the United States of America·Peter MergaertEva Kondorosi
Nov 17, 2006·Nature·Jonathan D G Jones, Jeffery L Dangl
May 18, 2007·Annual Review of Cell and Developmental Biology·Volker LipkaRalph Panstruga
Jun 15, 2007·The Plant Journal : for Cell and Molecular Biology·Kevin A T SilversteinKathryn A VandenBosch
Jul 11, 2008·Plant Physiology·Fatima AlkhalfiouiFrançoise Montrichard
May 12, 2009·Peptides·André de Oliveira Carvalho, Valdirene Moreira Gomes
Feb 27, 2010·Science·Willem Van de VeldePeter Mergaert
Sep 15, 2010·Plant Physiology·Ryoko Oono, R Ford Denison
Dec 29, 2011·Proceedings of the National Academy of Sciences of the United States of America·Fang XieJ Allan Downie
Feb 22, 2012·The Journal of Biological Chemistry·Andreas F HaagGail P Ferguson
Feb 23, 2012·Proceedings of the National Academy of Sciences of the United States of America·Nathan PumplinMaria J Harrison
May 9, 2012·Proceedings of the National Academy of Sciences of the United States of America·Sergey IvanovTon Bisseling
Mar 5, 2013·Annual Review of Plant Biology·Michael Udvardi, Philip S Poole
Feb 7, 2014·Proceedings of the National Academy of Sciences of the United States of America·Jon PentermanGraham C Walker
Mar 19, 2014·The Plant Journal : for Cell and Molecular Biology·Sumitha NalluKathryn A Vandenbosch
Apr 8, 2014·Proceedings of the National Academy of Sciences of the United States of America·Attila FarkasÉva Kondorosi
Feb 13, 2015·General Physiology and Biophysics·Krisztina NagyZsolt Szegletes
Jun 29, 2015·Current Opinion in Plant Biology·Gergely MarótiÉva Kondorosi
Sep 25, 2015·Proceedings of the National Academy of Sciences of the United States of America·Beatrix HorváthPéter Kaló
Sep 25, 2015·Proceedings of the National Academy of Sciences of the United States of America·Paul A PriceJoel S Griffitts
Nov 26, 2015·Proceedings of the National Academy of Sciences of the United States of America·Minsoo KimDong Wang
Jan 23, 2016·The New Phytologist·Aleksandr GavrinElena E Fedorova
Aug 24, 2016·Proceedings of the National Academy of Sciences of the United States of America·Mohammed ShababGraham C Walker
Dec 27, 2016·Current Biology : CB·Carolina Werner RibeiroPierre Frendo
Apr 26, 2017·Proceedings of the National Academy of Sciences of the United States of America·Jesús MontielÉva Kondorosi
Mar 1, 1990·Evolution; International Journal of Organic Evolution·Matt LavinJeffrey D Palmer
Jun 14, 2017·Proceedings of the National Academy of Sciences of the United States of America·Shengming YangHongyan Zhu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
Minsoo KimDong Wang
Proceedings of the National Academy of Sciences of the United States of America
Jesús MontielEva Kondorosi
© 2022 Meta ULC. All rights reserved