Toward a personalized therapy for panic disorder: preliminary considerations from a work in progress

Neuropsychiatric Disease and Treatment
Daniela Caldirola, Giampaolo Perna

Abstract

Although several treatment options for panic disorder (PD) are available, the best intervention for each individual patient remains uncertain and the use of a more personalized therapeutic approach in PD is required. In clinical practice, clinicians combine general scientific information and personal experience in the decision-making process to choose a tailored treatment for each patient. In this sense, clinicians already use a somehow personalized medicine strategy. However, the influence of their interpretative personal models may lead to bias related to personal convictions, not sufficiently grounded on scientific evidence. Hence, an effort to give some advice based on the science of personalized medicine could have positive effects on clinicians' decisions. Based on a narrative review of meta-analyses, systematic reviews, and experimental studies, we proposed a first-step attempt of evidence-based personalized therapy for PD. We focused on some phenomenological profiles, encompassing symptoms during/outside panic attacks, related patterns of physiological functions, and some aspects of physical health, which might be worth considering when developing treatment plans for patients with PD. We considered respiratory, cardiac,...Continue Reading

Citations

Jun 17, 2020·Expert Opinion on Pharmacotherapy·Daniela CaldirolaGiampaolo Perna
Aug 7, 2020·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Giampaolo Perna, Daniela Caldirola
Apr 24, 2021·Journal of Experimental Pharmacology·Daniela CaldirolaGiampaolo Perna

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Methods Mentioned

BETA
pharmacotherapy
BRT

Software Mentioned

PD
Is

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