Toward disease modification in multiple system atrophy: Pitfalls, bottlenecks, and possible remedies

Movement Disorders : Official Journal of the Movement Disorder Society
Florian KrismerG K Wenning

Abstract

Multiple system atrophy has recently attracted increased attention in basic and clinical research. Understanding of key pathophysiological mechanismshas improved; and, in the past decade, the first clinical trials aiming at diseasemodification were conducted. However, there is still no established interventional therapy available. In this review, the authors summarize recent advances, discuss bottlenecks and possible pitfalls of previous interventional studies, and suggest future research avenues.

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Citations

Jul 31, 2016·Movement Disorders : Official Journal of the Movement Disorder Society·Florian KrismerWerner Poewe
Feb 9, 2016·Movement Disorders : Official Journal of the Movement Disorder Society·Nadia StefanovaGregor K Wenning
Jul 28, 2016·Movement Disorders Clinical Practice·Han-Joon KimVictor S C Fung

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