Toward Disentangling the Multiple Nutritional Constraints Imposed by Planktothrix : The Significance of Harmful Secondary Metabolites and Sterol Limitation

Frontiers in Microbiology
Anke SchwarzenbergerDominik Martin-Creuzburg

Abstract

The harmful bloom-forming cyanobacterium Planktothrix is commonly considered to be nutritionally inadequate for zooplankton grazers, resulting in limited top-down control. However, interactions between Planktothrix and zooplankton grazers are poorly understood. The food quality of Planktothrix is potentially constrained by morphological properties (i.e., filament formation), the production of harmful secondary metabolites, and a deficiency in essential lipids (i.e., primarily sterols). Here, we investigated the relative significance of toxin production (microcystins, carboxypeptidase A inhibitors, protease inhibitors) and sterol limitation for the performance of Daphnia feeding on one Planktothrix rubescens and one P. agardhii wild-type/microcystin knock-out mutant pair. Our data suggest that the poor food quality of both Planktothrix spp. is due to deleterious effects mediated by various harmful secondary metabolites and that the impact of sterol limitation is partially or completely superimposed by toxicity. The significance of the different factors seems to depend on the metabolite profile of the considered Planktothrix strain and the Daphnia clone that is used for the experiments. The toxin-responsive gene expression (trans...Continue Reading

References

Jul 27, 2001·Applied and Environmental Microbiology·T RohrlackK Christoffersen
Oct 16, 2001·Toxicon : Official Journal of the International Society on Toxinology·J F BlomF Jüttner
Jun 21, 2003·Proceedings. Biological Sciences·Eric von ElertJean R Le Coz
Mar 10, 2004·The International Journal of Biochemistry & Cell Biology·Michelle M GehringerBrett A Neilan
May 14, 2005·Oecologia·Dominik Martin-CreuzburgEric von Elert
Sep 15, 2005·Environmental Microbiology·Thomas RohrlackUrsula Friberg-Jensen
Apr 4, 2008·Evolution; International Journal of Organic Evolution·Frida Ben-AmiDieter Ebert
May 1, 2009·Human Genomics·Vasilis VasiliouDaniel W Nebert
Dec 8, 2009·Environment International·L L Amado, J M Monserrat
May 9, 2012·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Nina SchlotzDominik Martin-Creuzburg
May 25, 2012·The Journal of Experimental Biology·Eric von ElertAnke Schwarzenberger
Nov 7, 2012·Oecologia·Marie-Elodie PergaOrlane Anneville
Jun 22, 2013·The Journal of Experimental Biology·Anke SchwarzenbergerEric Von Elert
Mar 20, 2014·Aquatic Toxicology·Thomas Sadler, Eric von Elert
Sep 10, 2014·BMC Genomics·Anke SchwarzenbergerEric von Elert
Sep 18, 2014·Journal of Chemical Ecology·Dominik Martin-CreuzburgAlexander Wacker
Mar 7, 2017·Frontiers in Microbiology·Elisabeth EntfellnerRainer Kurmayer
Oct 1, 1993·Oecologia·Joanna PijanowskaWinfried Lampert
Jan 23, 2018·Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology·Anke SchwarzenbergerEric Von Elert

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Citations

Nov 21, 2021·Environmental Science and Pollution Research International·Alane Silva de Aquino SantosAriadne do Nascimento Moura

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Methods Mentioned

BETA
PCR

Software Mentioned

500
STATISTICA

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