Toward Organism-scale Structural Biology: S-layer Reined in by Bacterial LPS.

Trends in Biochemical Sciences
Morgan Beeby

Abstract

Technical developments are unifying molecular and cellular biology. A recent electron cryotomography study by von Kügelgen et al. highlights the bright future for such studies, seamlessly integrating near-atomic resolution protein structures, organism-scale architecture, native mass spectrometry, and molecular dynamic simulations to clarify how the Caulobacter crescentus S-layer assembles on the lipopolysaccharides (LPS) of the cell surface.

Citations

May 21, 2021·Chemical Society Reviews·Yurou HuangJuyoung Yoon

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