Towards a dosimetric framework for therapeutic ultrasound

International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group
Adam ShawVolker Wilkens

Abstract

There is a need for a coherent set of exposure and dose quantities to describe ultrasound fields in media other than water (including tissue and tissue-simulating materials). This paper proposes an outline dosimetry scheme, with quantities for free field exposure, in situ exposure, dose (both instantaneous and cumulative) and effect, to act as a structure for organising a more complete set of definitions. It also presents findings from a survey of the views of the therapeutic ultrasound community which generally supports the principle of using modified free field quantities to describe the in situ field, and the prioritising of dose quantities which are related to heating and thermal mechanisms. Although there is no one-to-one relationship between any known ultrasound dose quantity and a specific biological effect, this can also be said of radiotherapy and other modalities where weighting factors have been developed to calculate the degree of equivalence between different tissues and radiation types. This same separation is recommended for ultrasound, provided that an appropriate set of recognised 'engineering' quantities can be established for exposure and dose quantities.

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Citations

Mar 5, 2016·Journal of Therapeutic Ultrasound·Adam ShawGail Ter Haar
Sep 3, 2016·Cancer Immunology, Immunotherapy : CII·Renske J E van den BijgaartGosse J Adema
Feb 1, 2019·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Petros X E MouratidisGail Ter Haar
Mar 12, 2015·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·Gail ter Haar
Aug 31, 2017·Scientific Reports·Francisco Javier Oyaga LandaDaniel Razansky
Feb 20, 2018··Francisco Javier Oyaga LandaRonald Sroka

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