Towards an assistive peripheral visual prosthesis for long-term treatment of retinitis pigmentosa: evaluating mobility performance in immersive simulations

Journal of Neural Engineering
Marc P ZapfG J Suaning

Abstract

The prospective efficacy of a future peripheral retinal prosthesis complementing residual vision to raise mobility performance in non-end stage retinitis pigmentosa (RP) was evaluated using simulated prosthetic vision (SPV). Normally sighted volunteers were fitted with a wide-angle head-mounted display and carried out mobility tasks in photorealistic virtual pedestrian scenarios. Circumvention of low-lying obstacles, path following, and navigating around static and moving pedestrians were performed either with central simulated residual vision of 10° alone or enhanced by assistive SPV in the lower and lateral peripheral visual field (VF). Three layouts of assistive vision corresponding to hypothetical electrode array layouts were compared, emphasizing higher visual acuity, a wider visual angle, or eccentricity-dependent acuity across an intermediate angle. Movement speed, task time, distance walked and collisions with the environment were analysed as performance measures. Circumvention of low-lying obstacles was improved with all tested configurations of assistive SPV. Higher-acuity assistive vision allowed for greatest improvement in walking speeds-14% above that of plain residual vision, while only wide-angle and eccentricity...Continue Reading

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Citations

Mar 10, 2020·Cyberpsychology, Behavior and Social Networking·Sarika GopalakrishnanRajiv Raman
Mar 23, 2017·Artificial Organs·Victor VergnieuxChristophe Jouffrais
Oct 27, 2017·Frontiers in Bioengineering and Biotechnology·Ying ZhaoXiaoqi Lv
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Jun 17, 2021·Disability and Rehabilitation. Assistive Technology·Sumukha UdupaCarol C Menassa
Aug 13, 2021·Asia-Pacific Journal of Ophthalmology·Mina IskanderLama A Al-Aswad

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