Towards an improved global understanding of treatment and outcomes in people with type 2 diabetes: Rationale and methods of the DISCOVER observational study program

Journal of Diabetes and Its Complications
Linong JiJesús Medina

Abstract

Contemporary global real-world data on the management of type 2 diabetes are scarce. The global DISCOVER study program aims to describe the disease management patterns and a broad range of associated outcomes in patients with type 2 diabetes initiating a second-line glucose-lowering therapy in routine clinical practice. The DISCOVER program comprises two longitudinal observational studies involving more than 15,000 patients in 38 countries across six continents. Study sites have been selected to be representative of type 2 diabetes management in each country. Data will be collected at baseline (initiation of second-line therapy), at 6months, and yearly during a 3-year follow-up period. The DISCOVER program will record patient, healthcare provider, and healthcare system characteristics, treatment patterns, and factors influencing changes in therapy. In addition, disease control (e.g. achievement of glycated hemoglobin target), management of associated risk factors (e.g. hypercholesterolemia and hypertension), and healthcare resource utilization will be recorded. Microvascular and macrovascular complications, incidence of hypoglycemic events, and patient-reported outcomes will also be captured. The DISCOVER program will provide i...Continue Reading

Citations

Jan 19, 2018·Journal of Diabetes·Ann M CarracherKelly L Close
Jun 20, 2019·Diabetes, Obesity & Metabolism·Kamlesh KhuntiMikhail Kosiborod
Aug 31, 2019·Diabetes, Obesity & Metabolism·Kamlesh KhuntiUNKNOWN DISCOVER investigators
Jun 7, 2020·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Naoto KatakamiUNKNOWN J-DISCOVER Study Group
Dec 21, 2017·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Naoto KatakamiUNKNOWN J-DISCOVER study group
Feb 12, 2021·ESC Heart Failure·Suzanne V ArnoldUNKNOWN DISCOVER investigators
Apr 15, 2021·Diabetes, Obesity & Metabolism·Kamlesh KhuntiUNKNOWN DISCOVER Investigators
Jul 13, 2021·Diabetes Research and Clinical Practice·Linong JiUNKNOWN DISCOVER Investigators
Jul 25, 2021·Diabetes Research and Clinical Practice·Antonio NicolucciUNKNOWN DISCOVER investigators
Dec 29, 2021·Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders·Mitsuyoshi TakaharaUNKNOWN J-DISCOVER study group

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