Towards an understanding of the link between environmental emissions and human body burdens of PCBs using CoZMoMAN

Environment International
Knut BreivikFrank Wania

Abstract

Different factors affect how organic contaminants released into the environment over time distribute and accumulate, enter various food-chains, and potentially cause toxic effects in wildlife and humans. A sound chemical risk assessment thus requires the determination of the quantitative relationship between emissions and human exposure. This study aimed to assess the extent of the quantitative and mechanistic understanding of the link between environmental emissions and human body burdens for polychlorinated biphenyls (PCBs) in the western part of the Baltic Sea drainage basin and to identify any remaining knowledge gaps. An integrated, non-steady state model calculating human body burden from environmental emissions (CoZMoMAN) was created by linking the multi-compartment environmental fate model CoZMo-POP 2 with the human food chain bioaccumulation model ACC-HUMAN. CoZMoMAN predicted concentrations of seven PCB congeners in 11 key model compartments to typically within a factor of 2 to 4 of measured values, although larger discrepancies are noted for soils and humans. We conclude that whereas the most important processes which link emissions of PCBs to human body burdens are quite well understood in this region, some critical...Continue Reading

References

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Citations

Mar 10, 2011·Chemical Research in Toxicology·Richard S JudsonDavid J Dix
Sep 7, 2013·Environmental Health Perspectives·Therese Haugdahl NøstTorkjel Manning Sandanger
Jun 21, 2011·Environment International·Anett GeislerKai-Uwe Goss
Jan 28, 2017·Environmental Science & Technology·Shizhen ZhaoAndrew J Sweetman
Dec 16, 2016·International Journal of Circumpolar Health·Khaled AbassArja Rautio
Mar 20, 2018·Environmental Science. Processes & Impacts·Michael S McLachlanMatthew MacLeod
Feb 20, 2020·Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment·Manon Pruvost-CouvreurGilles Rivière
Jan 8, 2014·Proceedings of the National Academy of Sciences of the United States of America·Josh NemanRahul Jandial
Oct 18, 2013·Environmental Science. Processes & Impacts·Ingjerd S KrogsethMartin Schlabach
Aug 14, 2010·Environmental Science & Technology·Emma UndemanMichael S McLachlan
Jul 13, 2021·Environmental Science. Processes & Impacts·Knut BreivikFrank Wania
Sep 30, 2014·Environmental Science & Technology·Xianming ZhangFrank Wania
Jun 7, 2018·Environmental Science & Technology·Shizhen ZhaoAndrew J Sweetman

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