Towards global consensus in the treatment of gastrointestinal stromal tumor.

Expert Review of Anticancer Therapy
Peter ReichardtMargaret von Mehren

Abstract

The contemporary clinical landscape of gastrointestinal stromal tumor (GIST) has evolved rapidly over the past several years. Widely used treatment guidelines--from the European Society of Medical Oncology (ESMO) and the National Comprehensive Cancer Network--have recently been updated and represent the most up-to-date, comprehensive tools guiding the optimal management of GIST. In these, and in other published guidelines, close alignment among recommendations now exists for many of the clinical issues relevant to GIST management--surgery, use of the tyrosine kinase inhibitors imatinib and sunitinib and the role of pre- and post-operative imatinib, among others. This trend towards a global consensus in the treatment of GIST is the result of a relatively large amount of new data across the spectrum of its management. However, for some clinical considerations, recommendations still partially deviate. This review examines clinical recommendations and opinions on the management of GIST in the context of the latest data in the field and with an eye towards a multidisciplinary approach including surgical oncology, medical oncology, pathology and diagnostic radiology. Points of consensus are highlighted. Expert opinion is presented on...Continue Reading

References

Dec 3, 1998·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·H ChenM A Choti
Jul 26, 2000·Hematology/oncology Clinics of North America·M L Taylor, D D Metcalfe
Nov 14, 2001·Lancet·A T van OosteromUNKNOWN European Organisation for Research and Treatment of Cancer Soft Tissue and Bone Sarcoma Group
Jul 3, 2002·Human Pathology·Christopher D M FletcherSharon W Weiss
Aug 16, 2002·The New England Journal of Medicine·George D DemetriHeikki Joensuu
Sep 14, 2002·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Samuel SingerJonathan A Fletcher
Jan 17, 2003·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·George D Demetri
May 5, 2004·Annals of Surgical Oncology·Burton L Eisenberg, Ian Judson
May 19, 2005·International Journal of Cancer. Journal International Du Cancer·Sebastian BauerJochen Schütte
Jun 2, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Christopher L CorlessMichael C Heinrich
Dec 24, 2005·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·P Hohenberger, E Wardelmann
Mar 22, 2006·Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie·Martin E BlacksteinUNKNOWN Canadian Advisory Committee on GIST
Apr 21, 2006·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Maria Debiec-RychterUNKNOWN Australasian GastroIntestinal Trials Group
May 20, 2006·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Chandrajit P RautMonica M Bertagnolli
Sep 8, 2006·Annals of Surgical Oncology·S BonvalotA Le Cesne
Dec 30, 2006·Seminars in Diagnostic Pathology·Markku Miettinen, Jerzy Lasota
May 2, 2007·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Robert S BenjaminChuslip Charnsangavej
Jun 15, 2007·International Journal of Clinical Oncology·Junichi HasegawaToshirou Nishida
Nov 15, 2007·Annals of Surgical Oncology·Imran HassanJohn H Donohue
Nov 28, 2007·Annual Review of Pathology·Christopher L Corless, Michael C Heinrich
Feb 1, 2008·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Charles D BlankeHeikki Joensuu
Oct 24, 2008·International Journal of Clinical Oncology·Toshirou NishidaUNKNOWN GIST Guideline Subcommittee
Mar 24, 2009·Lancet·Ronald P DematteoUNKNOWN American College of Surgeons Oncology Group (ACOSOG) Intergroup Adjuvant GIST Study Team
Jul 10, 2009·Annals of Oncology : Official Journal of the European Society for Medical Oncology·P G CasaliUNKNOWN ESMO Guidelines Working Group

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Citations

Nov 30, 2011·International Journal of Colorectal Disease·Alexander W BehamB Michael Ghadimi
Dec 3, 2013·Indian Journal of Surgical Oncology·M R Sreevathsa
Apr 10, 2013·Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine·M J Duffy
May 11, 2012·Cancer Imaging : the Official Publication of the International Cancer Imaging Society·Janine KalkmannUNKNOWN German GIST Imaging Working Group
Aug 15, 2013·Annals of Surgical Oncology·Cristina A MetildiJason K Sicklick
Aug 5, 2014·Memo·Piotr Rutkowski, Iwona Lugowska
Dec 15, 2015·Expert Opinion on Drug Safety·Piotr Rutkowski, Joanna Stępniak
Nov 30, 2011·The Surgeon : Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland·G H TseP J O'Dwyer
Nov 10, 2011·Journal of Surgical Oncology·Peter W T Pisters, Chiara Colombo
Jul 16, 2013·International Journal of Cancer. Journal International Du Cancer·M J DuffyC Sturgeon
Jul 16, 2015·Arquivos Brasileiros De Cirurgia Digestiva : ABCD = Brazilian Archives of Digestive Surgery·Eduardo Marcucci PracuchoAri de Almeida Prado
May 23, 2012·Dalton Transactions : an International Journal of Inorganic Chemistry·Gianni SavaAlberta Bergamo
May 10, 2013·Clinical Chemistry·Michael J Duffy, John Crown

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