PMID: 9166589Jun 1, 1997Paper

Towards interbreed IBD fine mapping of the mh locus: double-muscling in the Asturiana de los Valles breed involves the same locus as in the Belgian Blue cattle breed

Mammalian Genome : Official Journal of the International Mammalian Genome Society
S DunnerM Georges

Abstract

The Spanish "Asturiana" cattle breed is characterized by the segregation of a genetically determined muscular hypertrophy referred to as double-muscling or "culones". We demonstrate by linkage analysis that this muscular hypertrophy involves the mh locus previously shown to cause double-muscling in the Belgian Blue cattle breed, pointing towards locus homogeneity of this trait across both breeds. Moreover, using a twopoint and multipoint maximum likelihood approach, we show that flanking microsatellite markers are in linkage disequilibrium with the mh locus in both breeds albeit with different alleles. Finally, we discuss how allelic homogeneity across breeds might be exploited to achieve efficient genetic fine-mapping of the mh locus.

References

May 1, 1994·Mammalian Genome : Official Journal of the International Mammalian Genome Society·D VaimanP Martin
Mar 1, 1994·Nature Genetics·W BarendseN Zhang
Nov 1, 1995·Mammalian Genome : Official Journal of the International Mammalian Genome Society·C CharlierR Hanset
Jul 1, 1996·The Journal of Heredity·R Z MaH A Lewin
Oct 1, 1996·Genome Research·M Georges, L Andersson

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Citations

Mar 21, 1998·Mammalian Genome : Official Journal of the International Mammalian Genome Society·L GrobetM Georges
Jul 10, 1998·Mammalian Genome : Official Journal of the International Mammalian Genome Society·W CoppietersM Georges
Dec 21, 2012·BMC Biotechnology·Tingting ZhangZhiying Zhang
Dec 27, 2016·Frontiers in Veterinary Science·Eduardo Casas, Marcus E Kehrli
Aug 7, 2002·Journal of Animal Science·R G Mateescu, M L Thonney
Jan 20, 2007·The Journal of Experimental Biology·Yu-Chuan LiangBor-Rung Ou
Dec 13, 2005·Genome Research·James E Womack

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