Mar 22, 2020

Toxic assessment, growth disrupting and neurotoxic effects of red seaweeds' botanicals against the dengue vector mosquito Aedes aegypti L

Ecotoxicology and Environmental Safety
Rabia BibiMunawwer Rasheed


Application of synthetic pesticides over decades to control insects, pests, and disease vectors has resulted in negative impacts on environment and health. The current study assessed the toxicological effects of 12 botanicals obtained from 4 different red seaweeds against the dengue vector mosquito Aedes aegypti L. (Diptera: Culicidae). Four species of red seaweeds, namely Laurencia karachiana, Gracilaria foliifera, Jania rubens, Asparagopsis taxiformis, were collected from Karachi coast and extracted with hexane, dichloromethane and methanol. The efficiency of these extracts was determined by using a dose-response bioassay method against 4th instar larvae of Ae. aegypti. Separate investigations on the toxicity and IGI effects were done. Comparative studies showed that the hexane extracts induced more toxic effects. Based on the LC50 values, obtained after 24 h of treatments, hexane extract of J. rubens (HJ) exhibited toxic effects with LC50 32 μg/mL, (equivalent to GHS category 3), followed by G. foliifera (HG) (LC50 76.8 μg/mL). HJ also showed prominent neurotoxic effects within 1-6 h. Comparatively, higher morphological abnormalities and growth inhibiting (IGI) effects were obtained in the dichloromethane and methanol extrac...Continue Reading

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Mentioned in this Paper

Congenital Abnormality
Toxicity Tests
Jania rubens
Gracilaria foliifera