Toxicity and composition profiles of solid phase extracts of oil sands process-affected water

The Science of the Total Environment
Siqing YueJuliana Ramsay

Abstract

After fractionation using sequential solid phase extraction, the presence of toxic components in oil sands process-affected water (OSPW) was detected by the Microtox® acute toxicity assay using effect-directed analysis. The composition of each fraction was determined by high-resolution electrospray ionization-Orbitrap mass spectrometry. Partial least-squares discriminant analysis (PLS-DA) was used to determine which chemical constituents in all seven fractions co-varied most strongly with toxicity. Although O2 compounds with double bond equivalence (DBE) between 3 and 9 positively correlated with toxicity, C15-C18 O2-NAs with DBE=4 (tricyclic structure), as well as C14-C17 O2-NAs with DBE=3 (bicyclic structure), were found to be most likely associated with OSPW toxicity, consistent with published toxicity studies of surrogate NAs. O4, many O3 (i.e. possibly hydroxylated O2 c-NAs) and a few O2 compounds were found to negatively correlate with toxicity. The results demonstrate the utility of the fractionation and the PLS-DA approach for evaluating composition-response relationships in a complex mixture and also contribute to a better understanding of the toxic compounds in OSPW. These findings will help to focus study on the most...Continue Reading

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Dec 19, 2014·Environmental Science & Technology·Siqing YueJuliana A Ramsay

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Citations

Feb 14, 2021·The Science of the Total Environment·Monique C SimairJohn V Headley
Apr 28, 2021·The Science of the Total Environment·Angela Pinzón-EspinosaRakesh Kanda
May 18, 2019·The Science of the Total Environment·Bruce KilgourLiza Hamilton

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