Toxicity and oviposition deterrence of essential oils of Clinopodium nubigenum and Lavandula angustifolia against the myiasis-inducing blowfly Lucilia sericata

PloS One
S BediniBarbara Conti

Abstract

Cutaneous myiasis is a severe worldwide medical and veterinary issue. In this trial the essential oil (EO) of the Andean medicinal plant species Clinopodium nubigenum (Kunth) Kuntze was evaluated for its bioactivity against the myiasis-inducing blowfly Lucilia sericata (Meigen) (Diptera Calliphoridae) and compared with that of the well-known medicinal plant species Lavandula angustifolia Mill. The EOs were analysed and tested in laboratory for their oviposition deterrence and toxicity against L. sericata adults. The physiology of EO toxicity was evaluated by enzymatic inhibition tests. The antibacterial and antifungal properties of the EOs were tested as well. At 0.8 μL cm-2, both EOs completely deterred L. sericata oviposition up to 3 hours. After 24 h, the oviposition deterrence was still 82.7% for L. angustifolia and the 89.5% for C. nubigenum. The two EOs were also toxic to eggs and adults of L. sericata. By contact/fumigation, the EOs, the LC50 values against the eggs were 0.07 and 0.48 μL cm-2 while, by topical application on the adults, LD50 values were 0.278 and 0.393 μL per individual for C. nubigenum and L. angustifolia EOs, respectively. Inhibition of acetylcholine esterase of L. sericata by EOs (IC50 = 67.450 and 79...Continue Reading

References

Mar 1, 1997·International Journal for Parasitology·R L Tellam, V M Bowles
May 19, 2001·Microbes and Infection·T K GraczykM R Cranfield
Jul 12, 2002·Phytotherapy Research : PTR·H M A Cavanagh, J M Wilkinson
Dec 10, 2002·Memórias do Instituto Oswaldo Cruz·Fabíola Barbiéri HoletzBenedito Prado Dias Filho
Jul 1, 1961·Biochemical Pharmacology·G L ELLMANR M FEATHER-STONE
Jul 13, 2004·International Journal of Food Microbiology·Sara Burt
Mar 16, 2007·Australian Veterinary Journal·J RothwellS Williams
Dec 8, 2009·Brazilian Journal of Biology = Revista Brasleira De Biologia·D J PrettoM G A Oliveira
Apr 14, 2010·International Journal of Food Microbiology·Marziyeh ToloueeMehdi Razzaghi-Abyaneh
Sep 29, 2011·Annual Review of Entomology·Catherine Regnault-RogerJohn Thor Arnason
May 1, 2012·Veterinary Parasitology·R Wall
Aug 7, 2012·Journal of Food Science·Martha Cristina Portillo-RuizGuadalupe Virginia Nevárez-Moorillón
Oct 31, 2012·Australian Veterinary Journal·G W Levot
Sep 23, 2014·International Journal for Parasitology·R M SandemanV M Bowles
Feb 25, 2015·Frontiers in Microbiology·Marianne PerriconeAntonio Bevilacqua
Jul 30, 2015·Parasitology Research·Amandeep Singh, Zorawar Singh
Dec 17, 2015·Annual Review of Entomology·Martin J R HallJamie R Stevens
May 7, 2016·Journal of Veterinary Medical Education·Amelia R CornishPaul D McGreevy
Feb 15, 2017·Parasites & Vectors·Stefano BediniBarbara Conti
Sep 26, 2017·Advances in Parasitology·Clare A AnsteadRobin B Gasser
Nov 28, 2017·Scientific Reports·Ana Carolina M JunqueiraStephan C Schuster

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Methods Mentioned

BETA
dissection
Protein Assay

Software Mentioned

GraphPad Prism
SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.