PMID: 11345456May 10, 2001Paper

Toxicity of boron to rainbow trout: a weight-of-the-evidence assessment

Environmental Toxicology and Chemistry
G Loewengart

Abstract

From the large data set available on the toxicity of boron to aquatic organisms, the toxicity of boron to the early life stages of rainbow trout (Oncorhyncus mykiss) is the seminal issue relative to setting water quality criteria and effluent standards. Issues associated with the early life stage studies are the flat concentration-response curve, the low threshold of toxicity, and teratogenic effects observed. Recent laboratory and field studies offer new experimental data that make a weight-of-the-evidence assessment timely. In a re-examination of the effect of boron on the embryo-larval stage in rainbow trout and zebrafish, adverse effects due to boron deficiency are observed which decrease with increasing dose. It was found that low concentrations of boron stimulate embryonic growth in rainbow trout and increase the viability and survival of embryonic zebrafish. As boron concentration is further increased, the dose-response curve becomes flat as homeostatic processes are active; this is followed at higher doses by a new adverse response that increases with increasing dose. As a result, the dose-response relationship is U shaped, consistent with the characteristic shape of an essential micronutrient. Thus, effects originally ...Continue Reading

Citations

Feb 22, 2008·Environmental Health Perspectives·Jenny R LenkowskiKelly A McLaughlin
Jul 4, 2006·The Science of the Total Environment·D CrawA Todd
Feb 16, 2016·Water Science and Technology : a Journal of the International Association on Water Pollution Research·Burcu Ertit TaştanGönül Dönmez
Oct 9, 2008·Archives of Environmental Contamination and Toxicology·Gail M DethloffChristian E Schlekat

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