Toxicity of Herbs, Vitamins, and Supplements

Advances in Chronic Kidney Disease
Elliot Charen, Nikolas Harbord

Abstract

In the United States, the Food and Drug Administration regulates the efficacy and safety of pharmaceutical drugs. This government agency was formed in direct response to a mass poisoning and more than 100 deaths from kidney failure due to a medicinal toxic alcohol exposure. In contrast, the Food and Drug Administration also regulates the use of vitamins, minerals, herbs, or botanicals as dietary supplements, banning specific medical claims but requiring no documentation of efficacy. Safety of dietary supplements is only ensured through reporting of adverse events and rarely through intervention. Consumers should be aware that supplements may in fact contain actual pharmaceuticals or nothing of value and have significant toxic potential. Toxicity due to Chinese herbal medicines, aristolochic acid, amygdalin, hypervitaminosis D, and heavy metal contamination is reviewed.

References

Jan 28, 1982·The New England Journal of Medicine·C G MoertelJ P Davignon
Apr 29, 1998·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·L J Vanherweghem
Apr 18, 2008·Kidney International·Frédéric D DebelleJoëlle L Nortier
Oct 29, 2008·Evidence-based Complementary and Alternative Medicine : ECAM·Felicity L Bishop, G T Lewith
Dec 3, 2010·The Journal of Clinical Endocrinology and Metabolism·Hyesoo LoweJohn P Bilezikian
Jan 25, 2014·The Journal of Clinical Endocrinology and Metabolism·Maria G VogiatziUNKNOWN Drugs, and Therapeutics Committee of The Pediatric Endocrine Society
Dec 7, 2016·Kidney Diseases·Li Yang
Jan 24, 2017·Advanced Drug Delivery Reviews·Blessy GeorgeLauren M Aleksunes
Feb 22, 2017·Analytical Methods : Advancing Methods and Applications·Xin WeiYi-Ming Liu
Jun 18, 2017·Biological Trace Element Research·Xiao-Hua YangJiang-Hua Lai
Mar 3, 2018·British Journal of Clinical Pharmacology·Peter N Taylor, J Stephen Davies
Mar 13, 2018·International Journal of Occupational and Environmental Health·Marek A MikulskiLaurence J Fuortes
Apr 5, 2018·Clinical Journal of the American Society of Nephrology : CJASN·Bo YangClaudio Ronco
Apr 28, 2018·Biological Trace Element Research·Shadi KohzadiAfshin Maleki
Aug 24, 2018·Environmental Science and Pollution Research International·Narendra KumarNeetu Dwivedi
Mar 5, 2019·Seminars in Nephrology·Lawrence H Lash

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Citations

Jan 9, 2021·The American Journal of Chinese Medicine·Jun-Yan XiangQiuhong Xie
Feb 2, 2021·Gastroenterology Clinics of North America·Gerard E MullinAlyssa M Parian
Jul 30, 2021·Nephrology·Rajeevalochana ParthasarathyGeorgi Abraham

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