Dec 17, 2008

Toxicity of nanoparticulate and bulk ZnO, Al2O3 and TiO2 to the nematode Caenorhabditis elegans

Environmental Pollution
Huanhua WangBaoshan Xing

Abstract

Limited information is available on the environmental behavior and associated potential risk of manufactured oxide nanoparticles (NPs). In this research, toxicity of nanoparticulate and bulk ZnO, Al(2)O(3) and TiO(2) were examined to the nematode Caenorhabditis elegans with Escherichia coli as a food source. Parallel experiments with dissolved metal ions from NPs were also conducted. The 24-h median lethal concentration (LC(50)) and sublethal endpoints were assessed. Both NPs and their bulk counterparts were toxic, inhibiting growth and especially the reproductive capability of the nematode. The 24-h LC(50) for ZnO NPs (2.3 mg L(-1)) and bulk ZnO was not significantly different, but significantly different between Al(2)O(3) NPs (82 mg L(-1)) and bulk Al(2)O(3) (153 mg L(-1)), and between TiO(2) NPs (80 mg L(-1)) and bulk TiO(2) (136 mg L(-1)). Oxide solubility influenced the toxicity of ZnO and Al(2)O(3) NPs, but nanoparticle-dependent toxicity was indeed observed for the investigated NPs.

  • References25
  • Citations140

References

Mentioned in this Paper

Calcinus elegans
Fertility
Cyartonema elegans
Coleonyx elegans
Daphnia magna
Cestrum elegans
Clarkia unguiculata
Clathrulina elegans
Aluminum Measurement
Cardioglossa elegans

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