PMID: 6023266May 19, 1967Paper

Toxicity of Panamanian poison frogs (Dendrobates): some biological and chemical aspects

Science
J W Daly, C W Myers

Abstract

A small Neotropical frog, Dendrobates pumilio, undergoes interpopulational variation in color, degree of toxicity, size, and habits. Differences in body coloration encompass the visible spectrum from red to blue, as well as achromatic black and white. There are wide variations in the degree of toxicity, but these variations are not correlated with supposed warning colors. Extracts of skin yield two toxic compounds characterized as steroidal alkaloids with molecular formulae C(19)H(33)NO(2) and C(l9)H(33)NO(3). The rapid rate of divergent evolution among populations of this frog may result from isolation and chance restriction of original heterozygosity, with subsequent selection acting on different and greatly limited mixtures of alleles.

References

Jan 5, 1965·Journal of the American Chemical Society·J W DalyK Biemann
Jun 1, 1959·Archives of Biochemistry and Biophysics·V ERSPAMER
Jul 15, 1961·Experientia·C SCHOEPF
Jan 15, 1963·Experientia·G ABOAB, P V VIGNAIS
Jul 15, 1963·Experientia·F MAERKI, B WITKOP
May 29, 1964·Science·H S MOSHERH G FISCHER
Apr 9, 1962·Biochimica Et Biophysica Acta·F MARKIB WITKOP

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Citations

Feb 22, 2002·Rapid Communications in Mass Spectrometry : RCM·Stephen McCleanW Franklin Smyth
Apr 1, 1994·Journal of Chemical Ecology·J W DalyA Stanley Rand
Feb 16, 1988·European Journal of Pharmacology·G G SchofieldS R Ikeda
Dec 1, 1969·Toxicon : Official Journal of the International Society on Toxinology·J ShindelmanF A Fuhrman
Jan 1, 1978·Toxicon : Official Journal of the International Society on Toxinology·J W DalyC W Myers
Jan 1, 1978·Toxicon : Official Journal of the International Society on Toxinology·M Mensah-Dwumah, J W Daly
Jan 1, 1987·Toxicon : Official Journal of the International Society on Toxinology·J W DalyN Whittaker
Aug 11, 1992·Toxicon : Official Journal of the International Society on Toxinology·J W DalyJ F Cover
Oct 1, 1992·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·O SacchiO Belluzzi
Mar 23, 2004·Toxicon : Official Journal of the International Society on Toxinology·Márcia Renata MortariAntonio Sebben
Aug 19, 2007·The Journal of Organic Chemistry·Katrina S Woodin, Timothy F Jamison
Nov 11, 2006·Proceedings of the National Academy of Sciences of the United States of America·Paul J WeldonJohn W Daly
Oct 28, 2009·Proceedings of the National Academy of Sciences of the United States of America·Martine E Maan, Molly E Cummings
Jan 29, 2000·Proceedings. Biological Sciences·K SummersT Cronin
Nov 21, 2008·Proceedings. Biological Sciences·Jonathan D BlountPhilip A Stephens
Jul 11, 2012·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Joseph A TobiasBruce E Lyon
May 22, 2013·Frontiers in Zoology·Ivonne MeucheHeike Pröhl
Aug 21, 2012·Frontiers in Zoology·J Manuel Vidal-CorderoF Javier Ortiz-Sánchez
Oct 17, 2002·Proceedings of the National Academy of Sciences of the United States of America·John W DalyMaureen A Donnelly
Apr 1, 2006·Proceedings of the National Academy of Sciences of the United States of America·Catherine R DarstDavid C Cannatella
May 7, 2004·Proceedings of the National Academy of Sciences of the United States of America·Ralph A SaporitoJohn W Daly
May 16, 2007·Proceedings of the National Academy of Sciences of the United States of America·Ralph A SaporitoJohn W Daly
May 17, 2001·Proceedings of the National Academy of Sciences of the United States of America·K Summers, M E Clough
Dec 1, 1973·Experientia·E Zlotkin
Dec 1, 1967·Journal of Pharmaceutical Sciences·K K Chen, A Kovaríková
Feb 3, 2016·Zoology : Analysis of Complex Systems, ZACS·Erin M MurrayRalph A Saporito
Jun 24, 2011·Journal of Pharmaceutical and Biomedical Analysis·Yongmei HuWangfun Fong
Jun 17, 2015·Journal of Evolutionary Biology·K SummersA M M Stuckert
Oct 14, 2008·Toxicon : Official Journal of the International Society on Toxinology·John W DalyJulián Faivovich
Aug 21, 2007·Toxicon : Official Journal of the International Society on Toxinology·Ralph A SaporitoJohn W Daly
Dec 21, 2010·Evolution; International Journal of Organic Evolution·Andreas RudhAnna Qvarnström
Jan 29, 2011·Evolution; International Journal of Organic Evolution·Laura CrothersMolly Cummings
Jun 21, 2011·Journal of Morphology·Sabine MelzerPhillip J Bishop
Sep 10, 2010·Evolution; International Journal of Organic Evolution·Corinne L Richards-Zawacki, Molly E Cummings

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