May 1, 1977

Toxicity of selected antibiotics in vitreous replacement fluid

Annals of Ophthalmology
G A StainerG Fishman

Abstract

Experiments with rabbits demonstrated no toxic effects on the retina after vitrectomy when the infusion fluid contained either 20 microgram/ml chloramphenicol saline, 10 microgram/ml amikacin saline, 10 microgram/ml tobramycin saline, or 10 microgram/ml clindamycin saline. We found abnormal electroretinograms and abnormal histologic findings in eyes receiving vitreous replacement with these same drugs in higher concentrations.

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Mentioned in this Paper

Entire Retina
Antibiotic throat preparations
A.M.K
Antifungal Antibiotics, Topical
Retinal Diseases
Antibiotics, Gynecological
Vitreous Body Structure
Amikacin
Syntomycin
Dalacin C

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