PMID: 15379003Sep 24, 2004Paper

Toxicity of wide-range polarity fractions from wood smoke and diesel exhaust particulate obtained using hot pressurized water

Environmental Toxicology and Chemistry
Alena KubátováMatthew J Picklo

Abstract

Epidemiological and toxicological studies correlate the adverse health effects of particulate matter (PM) with the available information regarding their chemical characterization, which has focused on nonpolar organics (e.g., polycyclic aromatic hydrocarbons [PAHs]), which are limited to 15 to 50% of total organic carbon. To study both polar and nonpolar species, we have employed hot pressurized (liquid) water for the fractionation of diesel exhaust and wood smoke PM. In agreement with the results of previous studies, nonpolar fractions from both PM samples showed strong cytotoxicity (cell viability decreased to 50-60%) corresponding to the presence of PAHs. Surprisingly, similar decreases in cell viability were also found in polar fractions (50 degrees C) from both diesel exhaust and wood smoke PM. The midpolarity fractions (100-150 degrees C) from wood smoke PM also displayed high cytotoxicity corresponding to methoxyphenols and oxy-PAHs. Although the midpolarity fractions from diesel exhaust PM showed no cytotoxicity, genotoxicity was found in the 150 degrees C fraction, possibly corresponding to nitroaromatics. The present study demonstrates the suitability of hot pressurized water (as a single, nontoxic solvent) for the fr...Continue Reading

Citations

May 10, 2012·Journal of Exposure Science & Environmental Epidemiology·Daniela HaluzaManfred Neuberger
Jan 5, 2016·Environmental Science & Technology·Sujan FernandoDon Shaw
Feb 7, 2013·Environment International·Pavel ČuprJana Klánová
Aug 5, 2008·Toxicology and Applied Pharmacology·Anette KocbachPer E Schwarze
Oct 28, 2005·Journal of Environmental Monitoring : JEM·Artur Braun
Jun 26, 2009·Inhalation Toxicology·Mari SamuelsenMartinus Løvik
Mar 17, 2017·Environmental Science and Pollution Research International·Bérénice RancMarie-Odile Simonnot
Jun 18, 2017·Environmental Science and Pollution Research International·Pamela N MelkiDominique Courcot

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