Toxicological Evaluation of Essential Oils from Some Plants of Rutaceae Family

Evidence-based Complementary and Alternative Medicine : ECAM
Iram LiaqatNajma Arshad

Abstract

Essential oils are produced as secondary metabolites by aromatic plants, predominantly belonging to families Apiaceae, Lamiaceae, Myrtaceae, and Rutaceae. The family Rutaceae has great economic importance for its numerous edible fruits and essential oils. In the present study, essential oils of seven plants of family Rutaceae, Aegle marmelos, Murraya koenigii, Citrus reticulata Blanco, Zanthoxylum armatum, Skimmia laureola, Murraya paniculata, and Boenninghausenia albiflora, were used for their toxicological assessment. Seven groups of selected essential oils-treated Wistar rats were established against control group (n = 5) that received water for 14 days; animals were offered feed and water ad libitum and treated with essential oils at 400 mg/kg body weight. Hematological studies revealed significant elevation in TEC in animals treated with essential oils of M. koenigii, S. laureola, and B. albiflora, while an elevation in PCV and depletion in MCV were observed in animals treated with M. paniculata and B. albiflora, respectively. Serological investigations demonstrated significant depletion in triglycerides and elevation in blood sodium level in animals treated with essential oils of A. marmelos and C. reticulata Blanco. Boen...Continue Reading

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Citations

Feb 12, 2019·Bioscience, Biotechnology, and Biochemistry·Dahu LiHuating Dou
Jun 16, 2019·Animals : an Open Access Journal From MDPI·Pavel HorkyJiri Skladanka
May 10, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Bishnu JoshiWalter Luyten
Dec 12, 2020·Journal of Ethnopharmacology·Ajay SharmaDamanjit Singh Cannoo
Sep 1, 2021·Chemical Research in Toxicology·Guillermo FélixEder Lugo-Medina

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