Toxicology of Frequently Encountered Nonsteroidal Anti-inflammatory Drugs in Dogs and Cats: An Update

The Veterinary Clinics of North America. Small Animal Practice
Mary Kay McLean, Safdar A Khan

Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are used for their antipyretic, anti-inflammatory, and analgesic properties. Although most NSAIDs consist of a range of pharmacologically active agents with diverse chemical structures and properties, they have similar therapeutic and adverse effects associated with their use. Each year, the American Society for the Prevention of Cruelty to Animals Animal Poison Control Center (APCC) receives hundreds of cases involving acute accidental ingestion/overdose of NSAIDs in dogs and cats. This article provides an overview on the classification, uses, pharmacokinetics, mechanisms of action, and treatment of the most commonly encountered NSAIDs in dogs and cats.

Citations

Oct 3, 2020·Frontiers in Veterinary Science·Diyala S ShihadihChristophe Morisseau
Nov 30, 2020·Topics in Companion Animal Medicine·Vicky KarakitsouMathios E Mylonakis
Apr 9, 2021·The Veterinary Record·Joshua James Allen WalkerDavid John Walker
Nov 2, 2021·Journal of Veterinary Internal Medicine·Margaret E GruenB Duncan X Lascelles
Jan 18, 2022·Journal of Veterinary Pharmacology and Therapeutics·Josep SolàJosé Miguel Vela

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