PMID: 9738772Sep 17, 1998Paper

Toxin-mediated streptococcal and staphylococcal disease

Journal of the American Academy of Dermatology
S M Manders

Abstract

After several decades of seemingly decreasing virulence, streptococcal and staphylococcal infections have reemerged as a major source of morbidity and mortality. Within the past 2 decades, not only have well-established diseases such as rheumatic fever begun to reappear. but also many new entities, such as toxic shock syndrome, streptococcal toxic shock syndrome, recurrent toxin-mediated perineal erythema, and recalcitrant erythematous desquamating disorder have been described. Central to the renewed importance of these bacteria has been the production of circulating toxins, which often function as superantigens in causing the clinical manifestations, morbidity and mortality associated with these diseases.

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Related Concepts

Bacterial Toxins
Mucocutaneous Lymph Node Syndrome
Endotoxic Shock
Staphylococcal Infections
Staphylococcal Skin Infections
Staphylococcus aureus
Streptococcal Infections
Streptococcus
Bacteria, Flesh-Eating
Streptolysins

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