Toxins-useful biochemical tools for leukocyte research

Susana CubillosKatja Lehmann


Leukocytes are a heterogeneous group of cells that display differences in anatomic localization, cell surface phenotype, and function. The different subtypes include e.g., granulocytes, monocytes, dendritic cells, T cells, B cells and NK cells. These different cell types represent the cellular component of innate and adaptive immunity. Using certain toxins such as pertussis toxin, cholera toxin or clostridium difficile toxin, the regulatory functions of Gα(i), Gαs and small GTPases of the Rho family in leukocytes have been reported. A summary of these reports is discussed in this review.


Mar 1, 1992·Immunology Today·G A ZimmermanT M McIntyre
Oct 1, 1991·European Journal of Immunology·K E Chaffin, R M Perlmutter
Jan 1, 1991·Toxicon : Official Journal of the International Society on Toxinology·W MalorniC Ramoni
Mar 1, 1991·Immunopharmacology·N Grenier-BrossetteJ L Cousin
Oct 1, 1991·Infection and Immunity·W A FlegelH Northoff
Jun 1, 1989·Agents and Actions·S KassisN Hanna
Feb 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·P M LadP A Smiley
Jul 31, 1986·Biochemical and Biophysical Research Communications·M VergheseR Snyderman
May 1, 1988·Infection and Immunity·W DäubenerU Hadding
Apr 15, 1988·Biochemical and Biophysical Research Communications·W D Blackburn, L W Heck
Jun 1, 1968·Journal of Bacteriology·S J Klebanoff
Feb 1, 1981·Transplantation·M IntronaA Mantovani
Oct 27, 1995·The Journal of Biological Chemistry·D ZhouS Sozzani
Aug 1, 1995·The Journal of Experimental Medicine·J G Cyster, C C Goodnow
Dec 1, 1994·European Journal of Immunology·P AllavenaA Mantovani
Feb 1, 1994·Protein Science : a Publication of the Protein Society·E A MerrittW G Hol
Jan 15, 1994·Structure·P E SteinR J Read

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