Toxoplasma gondii-induced brachial plexus neuropathy after allogeneic hematopoietic stem cell transplantation

Transplant Infectious Disease : an Official Journal of the Transplantation Society
Jozefien De ClercqDries Deeren

Abstract

Brachial plexus neuropathy is a rare, but underdiagnosed condition, characterized by intense analgesic-resistant shoulder pain, followed by brachial plexus paresis and sensory symptoms. We present a case of brachial plexus neuropathy, induced by Toxoplasma gondii (T. gondii) 17 days after allogeneic hematopoietic stem cell transplantation (alloHSCT) in a patient with acute myeloid leukemia. The diagnosis was made based on the clinical presentation, magnetic resonance imaging (MRI) of the brachial plexus, and positive T. gondii polymerase chain reaction (PCR) in cerebrospinal fluid. The patient was treated with pyrimethamine, sulfadiazine, and levofolinic acid during 6 weeks, with a positive outcome.

References

Dec 23, 2004·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Rodrigo MartinoUNKNOWN Infectious Disease Working Party of the European Group for Blood and Marrow Transplantation
Mar 12, 2010·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Stef MeersJohan Maertens
Jan 10, 2014·Neurology·Jeroen J J van EijkHarry R Dalton
Jun 23, 2015·Current Opinion in Infectious Diseases·Kiran GajurelJosé G Montoya
Dec 15, 2015·Muscle & Nerve·Jeroen J J van EijkNens van Alfen
May 21, 2016·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Flonza IsaMini Kamboj
Jun 13, 2017·Transplant Infectious Disease : an Official Journal of the Transplantation Society·Kiran GajurelJose G Montoya
Aug 21, 2018·Annals of Indian Academy of Neurology·Yareeda SireeshaAngamuthu Kanikannan

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