PMID: 327784Jul 1, 1977Paper

TQ-ST segment mapping: critical review and analysis of current concepts

The American Journal of Cardiology
R P Holland, H Brooks

Abstract

Controversy and confusion surround many aspects of TQ-ST segment mapping today. Technical standards pertaining to the recording and measurement of the TQ-ST deflection have not been uniformly established nor has the correlative value of the deflection as an indicator of myocardial injury been clearly ascertained. The TQ-ST deflection is believed to originate primarily although not exclusively as a result of extracellular potassium accumulation in the ischemic region and subsequent establishment of a transmembrane potential gradient during diastole and systole at the ischemic boundary. Nonspatial factors (including electrolytes, antiarrhythmic agents, heart rate) influence the TQ-ST deflection by altering this gradient. Spatial factors (including ischemic area and shape, electrode location) alter the relative position of the ischemic boundary to the electrode site and as such can be analyzed with the solid angle theorem. Further study of the complex behavior of the TQ-ST segment deflection, particularly in the presence of pharmacologic intervention, is necessary before mapping techniques can be used reliably in clinical studies designed to quantitate and modify ischemic damage.

References

Aug 1, 1976·The American Journal of Cardiology·H Kambara, J Phillips
May 1, 1977·Progress in Cardiovascular Diseases·R P Holland, M F Arnsdorf
Oct 1, 1976·Circulation Research·M S Spach, R C Barr
Aug 1, 1976·The Journal of Cell Biology·C Peracchia, A F Dulhunty
Oct 1, 1976·Circulation·H A Fozzard, D S DasGupta
Nov 23, 1976·The American Journal of Cardiology·H K GoldP R Maroko
Apr 1, 1975·American Heart Journal·R H SellerC Swartz
Jan 1, 1975·Circulation Research·J KupersmithB F Hoffman
Nov 1, 1975·The American Journal of Cardiology·H BrooksL Resnekov
Mar 1, 1976·The Journal of Clinical Investigation·R P Holland, H Brooks
Jan 1, 1976·British Heart Journal·R M NorrisB N Singh
Dec 1, 1972·British Heart Journal·B N Datta, B B Gupta
Feb 10, 1967·Annals of the New York Academy of Sciences·B F Hoffman, D H Singer
Apr 1, 1971·The American Journal of Cardiology·E Braunwald
Oct 1, 1972·European Journal of Pharmacology·S J ChoiG J Kelliher
Jan 1, 1972·Journal of Electrocardiology·K N Manvi, M H Ellestad
Mar 1, 1973·The Journal of Physiology·T F McDonald, D P MacLeod

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Citations

Jun 21, 1996·Molecular and Cellular Biochemistry·C Nirmala, R Puvanakrishnan
Nov 1, 1983·Basic Research in Cardiology·B TörökT Simor
Dec 1, 1978·The American Journal of Cardiology·A H HarkenB Chance
Oct 1, 1982·Computers and Biomedical Research, an International Journal·A L Goldberger, V Bhargava
Jun 1, 1985·Computers and Biomedical Research, an International Journal·P Grøttum
Jan 1, 1985·Molecular Aspects of Medicine·J H BottingM J Walker
May 1, 1993·Computer Methods and Programs in Biomedicine·L I Titomir
Jun 1, 1995·Journal of the American College of Cardiology·P M Okin, P Kligfield
Jul 24, 2004·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·V Vimal, T Devaki
Jan 13, 2004·Journal of Electrocardiology·David KilpatrickD S Li
Apr 16, 1998·Journal of Electrocardiology·R S MacLeodB Taccardi
Aug 1, 1983·Journal of the American College of Cardiology·E J CamaraE P Shapiro
Sep 1, 1984·Journal of the American College of Cardiology·M HaraphongseB I Jugdutt
Jun 3, 2005·Journal of Cardiopulmonary Rehabilitation·Joy M KaplanPaul Kligfield
Feb 1, 1979·Australian and New Zealand Journal of Medicine·P L Thompson
Jan 1, 1995·Journal of Cardiovascular Electrophysiology·R S MacLeodB M Horácek
Nov 1, 1980·The Journal of Clinical Investigation·R N PinckardM S Olson
Dec 26, 2003·Circulation Journal : Official Journal of the Japanese Circulation Society·Eishun HoribeHisayoshi Fujiwara
May 15, 2013·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Abhro Jyoti Roy, P Stanely Mainzen Prince
Feb 25, 2009·Journal of Electrocardiology·David G StraussHåkan Arheden
Feb 16, 2011·Journal of Biochemical and Molecular Toxicology·V R Punithavathi, P Stanely Mainzen Prince
Apr 28, 2004·Autonomic Neuroscience : Basic & Clinical·René CardinalJ Andrew Armour
Jan 1, 1979·The American Journal of Cardiology·L H OpieW F Lubbe
Oct 1, 1979·The American Journal of Cardiology·A D NelsonJ Windham

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