Trabeculectomy-related complications in Olmsted County, Minnesota, 1985 through 2010

JAMA Ophthalmology
Jessica A OlayanjuCheryl L Khanna

Abstract

Trabeculectomy is the surgical standard of care for patients with medically refractory glaucoma. The use of antimetabolite agents, such as mitomycin, has increased the rate of complications after trabeculectomy. To determine the rate of trabeculectomy-related complications during a 25-year study. For this retrospective, population-based study, we enrolled the residents of Olmsted County, Minnesota, who underwent a trabeculectomy from January 1, 1985, through December 31, 2010, at the Mayo Clinic and Olmsted Community Hospital. Data were collected from August 2012 to September 2013 followed by data analysis through January 2014. After reviewing the patient records, we determined the occurrence of complications, including bleb leak, hypotony, hyphema, choroidal effusion, choroidal hemorrhage, blebitis, and endophthalmitis, as they relate to the mitomycin concentration administered during the operation. We reviewed relevant publications in Ovid, MEDLINE, and PubMed to identify studies representative of the reported trabeculectomy complication rate. Cumulative probabilities of short- and long-term complications, determined using the Kaplan-Meier method, and the relation to mitomycin concentration applied during trabeculectomy. In 3...Continue Reading

Citations

Apr 7, 2016·Journal of Ophthalmic & Vision Research·Shahin YazdaniElham Ghahari
Dec 23, 2015·Journal of Comparative Effectiveness Research·Anne L ColemanUNKNOWN RiGOR Study Group
Oct 16, 2016·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·A G M JünemannB Hohberger
Dec 3, 2016·Indian Journal of Ophthalmology·Thidarat LeeungurasatienDamrong Wiwatwongwana
Sep 1, 2017·Journal of Glaucoma·Ricardo Y AbeVital P Costa
Jul 5, 2018·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Martin Q Diep, Michele C Madigan
Mar 5, 2019·International Ophthalmology·Somar HasanJan Darius Unterlauft
Apr 18, 2019·Journal of Glaucoma·Moon Jeong LeeDavid S Friedman
Feb 19, 2020·Acta Ophthalmologica·Gauti JóhannessonEinar Stefánsson
Nov 26, 2015·Current Opinion in Ophthalmology·Andrea K Sawchyn, Mark A Slabaugh
Jun 9, 2019·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Anja-Maria DavidsMatthias Klamann
Dec 21, 2018·International Journal of Molecular Sciences·Éva CsőszJózsef Tőzsér
Jan 17, 2020·International Ophthalmology·Ramanjit SihotaVeena Pandey
Nov 24, 2016·Cell and Tissue Banking·Christopher HodgeCon Petsoglou
Dec 1, 2018·Vestnik oftalmologii·S Yu Petrov, A V Volzhanin
Aug 23, 2020·Vision·Michele NicolaiCesare Mariotti
Aug 10, 2020·Journal of Glaucoma·Ricardo A Paletta GuedesAlfredo Chaoubah
Nov 27, 2020·European Journal of Ophthalmology·Maryam YadgariNader Nassiri
Dec 4, 2020·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·L Bisorca-GassendorfK Januschowski
Apr 29, 2019·Survey of Ophthalmology·Qianqian WangDaniel Lee
May 10, 2019·Ophthalmic Research·Chiara Del NoceCarlo Enrico Traverso

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.