Trabeculotomy opening size and IOP reduction after Trabectome® surgery

Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie
Thomas WeckerChristian van Oterendorp

Abstract

Trabeculotomy with the Trabectome® is an effective surgical procedure to lower intraocular pressure (IOP). However, in some patients it does not lead to a significant IOP reduction despite a gonioscopically well visible opening of Schlemm's canal. This study investigated whether the size of the trabeculotomy opening and other parameters, including anterior chamber depth (ACD) are related to IOP reduction. Retrospective observational case series with 93 eyes of 93 patients who underwent Trabectome surgery. Trabeculotomy opening and ACD were measured with an anterior segment swept source OCT. IOP was taken pre-operatively and at a single follow-up visit [follow-up time 125 ± 66 days (mean ± SD)]. The relationship between IOP reduction and OCT parameters and possible confounding factors was analyzed in a multiple linear regression model. The trabeculotomy opening size did not correlate with IOP reduction (slope of regression line = 0.0016; 95% confidence interval of slope: -0.025 to 0.028). The same applied for all other parameters tested, including ACD, which showed a tendency towards better IOP reduction with a deeper AC (slope = -1.9; 95% confidence interval: -5.54 to 1.73). Comparison between the 1st and 4th quartile of the tr...Continue Reading

References

Aug 1, 1959·American Journal of Ophthalmology·H H UNGER, J ROHEN
May 11, 2005·Ophthalmology·Don S MincklerBrian A Francis
Feb 28, 2008·Current Opinion in Ophthalmology·Theodoros Filippopoulos, Douglas J Rhee
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Oct 26, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Jens F JordanMatthias Neuburger

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Citations

Dec 9, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·C DeubelJ Lübke
Nov 6, 2020·Japanese Journal of Ophthalmology·Masayuki Kasahara, Nobuyuki Shoji
Mar 7, 2021·Journal of Clinical Medicine·Masaki TanitoYotaro Matsuoka
Jul 13, 2021·Acta Ophthalmologica·John Tsia-Chuen KanBryan Chin Hou Ang

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