PMID: 9442462Jan 27, 1998Paper

Trace elements and chronic liver diseases

Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)
C LoguercioG Gialanella

Abstract

The relationships between chronic liver diseases and trace element (TE) contents are debated. Particularly, no defined data are available about the TE levels in viral liver disease patients with or without malnutrition. In this study we evaluated blood and plasma levels of various trace elements in patients with HCV-related chronic liver disease, at different stages of liver damage (8 patients with chronic hepatitis and 32 with liver cirrhosis) with or without malnutrition. We also studied 10 healthy volunteers as control group. We found that cirrhotic subjects had a significant decrease of blood levels of Zn and Se, independently on the nutritional status, whereas plasma levels of Fe were significantly reduced only in malnourished cirrhotic patients. Our data indicate that liver impairment is the main cause of the blood decrease of Se and Zn levels in patients with non alcoholic liver disease, whereas the malnutrition affects Fe levels only.

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Citations

Jun 4, 2008·Biological Trace Element Research·Emilio González-ReimersM Candelaria Martín-González
Feb 3, 2011·Biological Trace Element Research·Zarife KuloğluAydan Kansu
Mar 11, 2015·Journal of Clinical and Experimental Hepatology·Chantal Bémeur, Roger F Butterworth
May 17, 2000·The Science of the Total Environment·M Navarro-Alarcón, M C López-Martínez
Dec 25, 2002·Free Radical Biology & Medicine·Carmela Loguercio, Alessandro Federico
Jan 6, 2001·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·C LoguercioC Del Vecchio Blanco
May 16, 2009·Biological Trace Element Research·Emilio González-ReimersFrancisco Santolaria-Fernández
Apr 7, 2007·Digestive Diseases and Sciences·Ioannis StamoulisStamatios Theocharis
Jul 29, 2005·The American Journal of Pathology·Lipeng WangY James Kang
Sep 21, 2010·Nutrition Research·Manuel Martínez-PeinadoMiguel Navarro-Alarcón
Aug 19, 2007·Free Radical Biology & Medicine·Scott SeronelloJinah Choi
Jul 11, 2008·International Journal of Dermatology·David James NajarianAmy S Pappert
Jan 18, 2003·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Ahmet KalkanNamik Kemal Bingol
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Feb 28, 2013·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Fabiola RusoloSusan Costantini
Jun 30, 2014·Biological Trace Element Research·Salma Aslam ArainAbdul Haleem Panhwar
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Jan 18, 2017·Biological Trace Element Research·Dalia A OmranAyman Yosry
Jan 27, 2019·Scientific Reports·Joseph GeorgeMutsumi Tsuchishima

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