Abstract
Although various proteins and some electrolytes have been measured in human saliva, little systematic data about the major and minor elemental components of this body fluid have been obtained. In order to obtain such data, concentrations of C, Na, P, Cl, K, Ca, Sc, Cr, Fe, Co, Zn, Se, Br, Rb, Sb, I, and Cs in human parotid saliva were measured by instrumental nuclear methods. The data obtained confirmed the relative lack of Zn in saliva of patients with hypogeusia (decreased taste acuity) and suggested that concentrations of Na, Cl, Br, and Ca followed the order: normals greater than hypogeusia greater than hyposmia (decreased smell acuity). To compare concentrations of elements in saliva with those in blood and urine, absolute concentrations were normalized to that of Na through the use of a concept called an enrichment factor. On this basis, parotid saliva is relatively depleted in Se, Zn, and Fe and enriched for most other elements relative to blood plasma indicating that the fluid is not simply a transudate of blood plasma. Using this same technique, saliva composition was found more similar to urine than blood plasma, being relatively depleted in Se, Cs, and Co, being enriched in I, Br, and Cr and having about the same rel...Continue Reading
References
Jan 7, 1977·Science·A M LawrenceL Kirsteins
Aug 21, 1976·Lancet·F ReynoldsS E Smith
Jan 1, 1978·Annual Review of Biochemistry·R A Bradshaw
Jul 1, 1978·Journal of Dental Research·J A Mangos
Dec 1, 1979·Journal of Dental Research·M Z MarderI D Mandel
Jan 1, 1979·Annual Review of Biochemistry·G Carpenter, S Cohen
Jul 1, 1978·International Journal of Radiation Oncology, Biology, Physics·K L Mossman, R I Henkin
Nov 1, 1976·The American Journal of the Medical Sciences·R I HenkinM Raff
Jan 1, 1976·Experientia·A D LandmanE T Pritchard
Feb 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·R I HenkinH Edelhoch
Aug 1, 1986·Biochemical Medicine and Metabolic Biology·J S Law, R I Henkin
Mar 1, 1985·The American Journal of Clinical Nutrition·R A AndersonM M Polansky
Jan 1, 1973·Journal of Oral Pathology·D Orstavik, F W Kraus
Jan 1, 1966·Pflügers Archiv für die gesamte Physiologie des Menschen und der Tiere·H HolzgreveA Vogel
Dec 1, 1969·Endocrinology·J M RosnerD P Cardinali
Jul 1, 1973·Analytical Chemistry·N K ArasG J Lutz
Jun 1, 1974·Analytical Chemistry·I OlmezW H Zoller
Mar 1, 1972·Annals of Internal Medicine·R I HenkinC F Mattern
Aug 1, 1970·Endocrinology·A L WeinerE A Sweeney
Oct 26, 1984·Science·J E GroopmanR C Gallo
Oct 1, 1980·Journal of Clinical Pathology·I Chanarin
Feb 28, 1983·Biochemical and Biophysical Research Communications·R F TroxlerF G Oppenheim
Apr 1, 1983·Biochemical Medicine·A R Shatzman, R I Henkin
Sep 1, 1984·Metabolism: Clinical and Experimental·R P Agarwal, R I Henkin
May 1, 1984·The American Journal of Clinical Nutrition·O A Levander, V C Morris
Feb 1, 1983·The Journal of Nutrition·R A AndersonW H Glinsmann
Jun 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·A R Shatzman, R I Henkin
Jan 1, 1980·Critical Reviews in Clinical Laboratory Sciences·I D Mandel
Nov 1, 1964·The Journal of Pediatrics·W S CHERNICKG J BARBERO
Mar 29, 1960·Annals of the New York Academy of Sciences·Y ITO
Citations
May 26, 2005·Biochemical and Biophysical Research Communications·Haleli Sharir, Michal Hershfinkel
Jun 28, 2007·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Clare F HodkinsonJulie M W Wallace
Jun 23, 1999·British Journal of Sports Medicine·J L ChicharroA Lucía
Aug 28, 2012·Journal of Oral and Maxillofacial Pathology : JOMFP·Bhargavi Krishna Ayinampudi, Malathi Narsimhan
Sep 28, 2014·Biological Trace Element Research·Ahmad Sheibaninia
Sep 18, 1998·Sports Medicine·J L ChicharroR Ureña
Jul 1, 1995·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·J P Dehaye
Feb 9, 2012·Archives of Oral Biology·Robert I Henkin, Irina Velicu
Mar 13, 2014·International Archives of Occupational and Environmental Health·Bernhard MichalkeGerhard Scherer
May 9, 2001·Biochimica Et Biophysica Acta·H GusmanF G Oppenheim
Apr 25, 2019·Pathogens·Spyridoula-Angeliki NikouJonathan P Richardson
Mar 30, 2019·Biological Trace Element Research·Susana PadoinSolange de Paula Ramos