Tracheal agenesis without esophageal fistula: genetic, resuscitative, and pathological issues

Journal of Pediatric Surgery
Daniele De LucaVincenzo Arena

Abstract

An exceptional case of tracheal agenesis with no communication with the esophagus is described. This malformation needs surgical airway approach and is hardly classifiable. We analyzed the literature and our institutional data: this resulted to be the first case of such anatomical variant. Genetic and pathological issues are reviewed: recent genetic data seem to explain this malformation. We also reviewed the available literature about prenatal presentation. Because prenatal diagnosis is difficult to achieve and current guidelines for neonatal resuscitation do not provide any recommendation, the resuscitative team may not be prepared for managing such a case. Usefulness of uncommon resuscitative maneuvers is discussed: a promptly performed surgical tracheotomy is the only mean to ventilate such a baby.

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Citations

May 19, 2011·European Journal of Pediatrics·Ulrich KrauseThomas Paul
Sep 16, 2011·European Journal of Pediatrics·Maurike D de Groot-van der MoorenRuurd M van Elburg
Jul 16, 2016·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·P LangeT Ansari
Jan 8, 2016·The Journal of Laryngology and Otology·H MohammedM Wickstead
Oct 9, 2020·The Annals of Otology, Rhinology, and Laryngology·Alexander J StraughanLyuba Gitman

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