Tracheal autograft revascularization and transplantation

Archives of Otolaryngology--head & Neck Surgery
P R DelaereL Feenstra

Abstract

No vascular pedicle can be obtained reasonably to provide revascularization of a tracheal graft by direct microvascular suture. This study is a morphometric analysis of epithelial regeneration, submucosal revascularization, and mucosal thickness of isolated, tracheal segments revascularized by a lateral thoracic fascial flap. The purpose of the first part of the study is to determine the optimal period of tracheal viability after isolation and revascularization. The second part consisted of a reimplantation of the revascularized autograft into its original tracheal location. A tracheal segment was excised in 30 animals, and the segment was wrapped in the lateral thoracic fascia. The segments were reviewed histologically and morphometrically 2 to 28 days after graft isolation and after injection of the lateral thoracic artery with a blue silicone dye. Twelve grafts were reimplanted. Six segments were reinserted in the original direction and six segments were reinserted in the opposite direction. Tracheal airway clearance was studied by observation of the movement of carbon particles placed at different locations on the native and transplanted tracheal mucosa. Tracheal autograft revascularization and reepithelialization. Histolog...Continue Reading

Citations

Mar 26, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Ilir HysiBrigitte Jude
Apr 1, 1996·The Laryngoscope·P R DelaereL Feenstra
Feb 1, 1996·Academic Radiology·R HermansA L Baert
Sep 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·P R DelaereL Feenstra
Jun 28, 2005·Clinics in Plastic Surgery·Ralph W Gilbert, Peter C Neligan
Sep 18, 2001·The Annals of Otology, Rhinology, and Laryngology·P R DelaereB Van Den Hof
Apr 14, 2012·Current Opinion in Pulmonary Medicine·Pierre R Delaere

❮ Previous
Next ❯

Related Concepts

Related Feeds

Allogenic & Autologous Therapies

Allogenic therapies are generated in large batches from unrelated donor tissues such as bone marrow. In contrast, autologous therapies are manufactures as a single lot from the patient being treated. Here is the latest research on allogenic and autologous therapies.

Related Papers

The Journal of Thoracic and Cardiovascular Surgery
P R DelaereL Feenstra
The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Toshiaki MasaokaYasuhisa Shimazaki
The Annals of Thoracic Surgery
R NakanishiT Takachi
© 2021 Meta ULC. All rights reserved