Tracheal dilatation by halothane and enflurane in man

Journal of Anesthesia
I YasudaT Tajima

Abstract

The effect of halothane and enflurane on tracheal tone were studied in 21 patients during the induction of anesthesia. Endotracheal tube cuff pressure was used to measure tracheal tone. Anesthesia, maintained by nitrous oxide 70% in oxygen, was supplimented with succinylcholine drip infusion to immobilize the patient. Ventilation was controlled by a Volume-preset ventilator. In the halothane group, the initial cuff pressure was 14.8 +/- 1.3 (mean +/- SE) cmH(2)O but 10 min after 0.15 mg/kg of pancuronium injection, it increased to 21.7 +/- 2.3 cmH(2)O (control). Ten min after inhalation of 0.75% of halothane, cuff pressure decreased to 14.7 +/- 2.3 cmH(2)O (34 +/- 11% decrease from the control value). In the enflurane group, the initial cuff pressure was 17.6 +/- 1.8 cmH(2)O and it increased to 21.0 +/- 1.7 cmH(2)O (control) 10 min after pancuronium injection. Ten min after 1.7% of enflurane inhalation, cuff pressure decreased to 17.1 +/- 2.3 cmH(2)O (23.9 +/- 6% decrease from the control value). Halothane and enflurane produced similar tracheal dilatation in healthy individuals.

References

Dec 1, 1978·Anesthesiology·F S Brauer, C R Ananthanarayan
Nov 1, 1978·Anesthesia and Analgesia·C A Hirshman, N A Bergman
Aug 1, 1978·Anesthesiology·I YasudaM Satoh
Sep 1, 1973·Anesthesia and Analgesia·A B DobkinA A Levy
May 1, 1973·Anesthesia and Analgesia·A B DobkinP H Byles
Sep 1, 1968·Anesthesiology·R W PattersonE M Papper
Feb 1, 1983·Anesthesiology·C A Hirshman
Apr 1, 1984·Anesthesiology·S KorenagaY Ito
Feb 1, 1982·Anesthesiology·C A HirshmanH Downes

❮ Previous
Next ❯

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.