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Tracking global changes induced in the CD4 T cell receptor repertoire by immunization with a complex antigen using short stretches of CDR3 protein sequence.

bioRxiv

Jan 17, 2014

Niclas ThomasBenny M Chain

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Abstract

The clonal theory of adaptive immunity proposes that immunological responses are encoded by increases in the frequency of lymphocytes carrying antigen-specific receptors. In this study, we measure the frequency of different TcRs in CD4+ T cell populations of mice immunized with a comple...read more

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Immunization Domain
Study
Immunization
Alpha-beta T-Cell Receptor
CEREBELLAR DEGENERATION-RELATED AUTOANTIGEN 3
Specimen Type - Lymphocytes
Antibody Repertoire
Adaptive Immunity
Spastic Syndrome
Clone
2
5
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  • Tracking global changes induced in the CD4 T cell receptor repertoire by immunization with a complex antigen using short stretches of CDR3 protein sequence.

    bioRxiv

    Jan 17, 2014

    Niclas ThomasBenny M Chain

    PMID: 990001883

    DOI: 10.1101/001883

    Abstract

    The clonal theory of adaptive immunity proposes that immunological responses are encoded by increases in the frequency of lymphocytes carrying antigen-specific receptors. In this study, we measure the frequency of different TcRs in CD4+ T cell populations of mice immunized with a comple...read more

    Mentioned in this Paper

    Immunization Domain
    Study
    Immunization
    Alpha-beta T-Cell Receptor
    CEREBELLAR DEGENERATION-RELATED AUTOANTIGEN 3
    2
    5

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