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Tracking global changes induced in the CD4 T cell receptor repertoire by immunisation with a complex antigen using local sequence features of CDR3 protein sequence

bioRxiv

Jan 17, 2014

Niclas ThomasBenny Chain

Abstract

The clonal theory of adaptive immunity proposes that immunological responses are encoded by increases in the frequency of lymphocytes carrying antigen-specific receptors. In this study, we measure the frequency of different TcRs in CD4+ T cell populations of mice immunized with a comple...read more

Mentioned in this Paper

Lymphocyte Count Measurement
Immunization
Protein Domain
Antibody Repertoire
Clone
Specimen Type - Lymphocytes
Sequencing
Lymphocyte
Laboratory mice
CEREBELLAR DEGENERATION-RELATED AUTOANTIGEN 3
2
5
Paper Details
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Tracking global changes induced in the CD4 T cell receptor repertoire by immunisation with a complex antigen using local sequence features of CDR3 protein sequence

bioRxiv

Jan 17, 2014

Niclas ThomasBenny Chain

PMID: 990001883

DOI: 10.1101/001883

Abstract

The clonal theory of adaptive immunity proposes that immunological responses are encoded by increases in the frequency of lymphocytes carrying antigen-specific receptors. In this study, we measure the frequency of different TcRs in CD4+ T cell populations of mice immunized with a comple...read more

Mentioned in this Paper

Lymphocyte Count Measurement
Immunization
Protein Domain
Antibody Repertoire
Clone
Specimen Type - Lymphocytes
Sequencing
Lymphocyte
Laboratory mice
CEREBELLAR DEGENERATION-RELATED AUTOANTIGEN 3
2
5

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