Tract length predicts successful closure with anal fistula plug in cryptoglandular fistulas

Diseases of the Colon and Rectum
Michael F McGeeConor P Delaney

Abstract

Collagen anal fistula plug treatment of transsphincteric fistulas produces variable results. The purpose of our study was to determine whether long-tract fistulas (>4 cm) correlated with successful closure. All patients undergoing transsphincteric cryptoglandular fistula repair with anal fistula plugs were enrolled in a prospective database. Patients with Crohn's disease were excluded. Fistula tract length was measured intraoperatively by subtracting the remaining plug length from the original plug size. All procedures used standardized techniques and postoperative care pathways. The primary outcome was complete fistula closure assessed through both postoperative outpatient visits and a follow-up telephone questionnaire. Forty-one patients with 42 fistula tracks were enrolled over a 39-month period. Complete closure was achieved in 18 of 42 (43%) fistulas at a mean follow-up of 25 months. Closure was not associated with gender, age, tract location, duration of seton, or length of follow-up. Successful closure was significantly associated with increased tract length, because fistulas longer than 4 cm were nearly 3 times more likely to heal compared with shorter fistulas ((14/23, 61%) vs (4/19, 21%), P = .004; relative risk = 2.8...Continue Reading

References

Oct 1, 1990·The British Journal of Surgery·P Lewis, D C Bartolo
Jul 1, 1990·Diseases of the Colon and Rectum·K UstynoskiI T Khubchandani
Jul 1, 1986·Diseases of the Colon and Rectum·A ChristensenJ Christiansen
Jan 4, 1998·Diseases of the Colon and Rectum·Y H HoF Seow-Choen
Feb 14, 1998·The British Journal of Surgery·G V Miller, P J Finan
Aug 11, 1998·The European Journal of Surgery = Acta Chirurgica·A Dziki, M Bartos
Dec 11, 2002·Diseases of the Colon and Rectum·Toyooki SonodaVictor W Fazio
Sep 16, 2003·Diseases of the Colon and Rectum·Gordon N BuchananRichard G Cohen
Nov 18, 2003·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·M WesterterpW F van Tets
Feb 24, 2004·Diseases of the Colon and Rectum·Rasmy LoungnarathJames W Fleshman
Sep 1, 2004·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·T M HammondP J Lunniss
Jan 20, 2006·Diseases of the Colon and Rectum·Eric K JohnsonDavid N Armstrong
Sep 26, 2006·Diseases of the Colon and Rectum·Lynn O'ConnorDavid N Armstrong
Nov 4, 2006·Diseases of the Colon and Rectum·Bradley J ChampagneDavid N Armstrong
Feb 27, 2007·Journal of Surgical Education·C Neal Ellis
Mar 12, 2008·Diseases of the Colon and Rectum·Alex J KyErin K Ly
Apr 1, 2008·World Journal of Surgery·D A LawesT M Young-Fadok
Jun 4, 2008·Diseases of the Colon and Rectum·Dimitrios ChristoforidisAnders Mellgren
Mar 11, 2009·Diseases of the Colon and Rectum·Dimitrios ChristoforidisAnders F Mellgren
Mar 13, 2009·Diseases of the Colon and Rectum·Bashar SafarSteven D Wexner
Aug 20, 2009·Diseases of the Colon and Rectum·Thilo SchwandnerMarkus Hirschburger

❮ Previous
Next ❯

Citations

Jul 16, 2010·Diseases of the Colon and Rectum·Dimitrios Christoforidis
Feb 4, 2012·Current Gastroenterology Reports·Dawn M Wiese, David A Schwartz
Jun 5, 2013·The Indian Journal of Surgery·Parvez Sheikh
Oct 8, 2011·Diseases of the Colon and Rectum·Fernando de la PortillaJosé M Sánchez-Gil
Jun 19, 2012·Diseases of the Colon and Rectum·Ariane M AbcarianHerand Abcarian
Oct 10, 2012·Diseases of the Colon and Rectum·Ulrik G WallinStanley M Goldberg
Feb 9, 2013·Diseases of the Colon and Rectum·Wendy Y LiuRavin R Kumar
Aug 31, 2011·World Journal of Gastroenterology : WJG·Haig Dudukgian, Herand Abcarian
Apr 25, 2012·Techniques in Coloproctology·S ChanC R Cohen
Mar 1, 2012·World Journal of Surgery·J BlumettiH Abcarian
Nov 28, 2012·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·W Heitland
Sep 10, 2015·Journal of Crohn's & Colitis·A SenéjouxUNKNOWN Groupe d’Etude Thérapeutique des Affections Inflammatoires du tube Digestif [GETAID]
Mar 13, 2014·Current Problems in Surgery·Jan Rakinic, Venkateswara Prasad Poola
Nov 7, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Sunil K NarangNeil J Smart
Mar 20, 2012·Cirugía española·José V Roig, Juan García-Armengol
Jan 6, 2016·The Indian Journal of Surgery·P K ChowbeyM Baijal
Oct 17, 2012·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·J G HanX Q Yang
Aug 29, 2013·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·K-K TanM J Solomon
Feb 11, 2014·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·J BlomP-O Nyström
Feb 3, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·O M FisherA Nocito
May 10, 2015·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·Andreas Ommer
Jan 9, 2015·International Journal of Colorectal Disease·F CadedduG Milito
Mar 19, 2016·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Christos KontovounisiosSteven Wexner
Sep 19, 2015·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·David R Rosen, Andreas M Kaiser
Dec 7, 2018·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·H LinW Hu
Mar 21, 2019·Annals of Coloproctology·Melina Svraka HansenJens Andersen
May 23, 2019·Health Technology Assessment : HTA·David G JayneLaura Magill
Aug 30, 2016·World Journal of Gastroenterology : WJG·Carlo RattoAngelo Parello
Mar 3, 2017·Langenbeck's Archives of Surgery·Andreas OmmerBernhard Strittmatter
Nov 23, 2020·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Mauricio Sarmiento-CobosSteven D Wexner
Nov 25, 2011·Deutsches Ärzteblatt International·Andreas OmmerUNKNOWN German Society for General and Visceral Surgery
Nov 7, 2020·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·Ursula Aho FältLouis B Johnson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.